Research

Pharmacy Practice
Pharmacy Practice
Department of Pharmacy Practice
Course of Medical and Dental Sciences
http://www.ph.nagasaki-u.ac.jp/lab/hospital/index-e.html
Teaching Staff
Name Position E-mail Tel Fax
Mikiro Nakashima, Ph. D.
Professor
mikirou@nagasaki-u.ac.jp +81-95-819-8570 +81-95-819-8572
Kaname Ohyama, Ph. D.
Associate Professor
k-ohyama@nagasaki-u.ac.jp +81-95-819-8569
Tomoaki Kurosaki, Ph. D.
Assistant Professor
kurosaki@nagasaki-u.ac.jp
Research
  • Propose use of PXB-mice® as a reliable tool for drug repositioning screening against liver disease
  • Screening disease-specific immune complex antigens for autoimmune diseases and cancers
  • Measure the concentration of drugs binding to their targets
Selected Publications
  1. Aibara N, Ichinose K, Baba M, Nakajima H, Satoh K, Atarashi R, Kishikawa N, Nishida N, Kawakami A, Kuroda N, Ohyama K: Proteomic approach to profiling immune complex antigens in cerebrospinal fluid samples from patients with central nervous system autoimmune diseases. Clin Chim Acta 484: 26-31, 2018
  2. Ishikawa T, Ohtaki H, Mizuta S, Kuriyama M, Onomura O, Higuchi N, Nakashima MN, Nakashima M, Ohyama K: Computational study of the competitive binding of valproic acid glucuronide and carbapenem antibiotics to acylpeptide hydrolase. Drug Metab Pharmacokinet 32: 201-207, 2017
  3. Ohyama K, Yoshimi H, Aibara N, Nakamura Y, Miyata Y, Sakai H, Fujita F, Imaizumi Y, Chauhan AK, Kishikawa N, Kuroda N: Immune complexome analysis reveals specific and frequent presence of immune complex antigens in lung cancer patients: A pilot study. Int J Cancer 140: 370-380, 2017
  4. Araki R, Nakashima M, Teshima M, Owaki Y, Nakashima MN, Uematsu M, Kitaoka T, Nakamura T, Kitahara T, Sasaki H: Investigation of protective effects of sodium hyaluronate eyedrop agaist comeal epithelial disorders using an electophysiological method. J Ocul Pharmacol Ther 28: 251-258, 2012
  5. Ohyama K, Ueki Y, Kawakami A, Kishikawa N, Tamai M, Osaki M, Kamihira S, Nakashima K, Kuroda N: Immune complexome analysis of serum and its application in screening for immune complex antigens in rheumatoid arthritis. Clin Chem 57: 905-909, 2011
Research Paper List