Research
Department of Pharmaceutics
Teaching staffs
| Name, Position | Email *convert [a] to @ |
Tel | Fax |
|---|---|---|---|
| Koyo Nishida, Ph. D. Professor | koyo-n[a]nagasaki-u.ac.jp | +81-95-819-8566 | +81-95-819-8566 |
| Shintaro Fumoto, Ph. D. Associate Professor | sfumoto[a]nagasaki-u.ac.jp | +81-95-819-8568 | +81-95-819-8568 |
| Hirotaka Miyamoto, Ph. D. Assistant Professor |
hmiyamoto[a]nagasaki-u.ac.jp | +81-95-819-8567 | +81-95-819-8567 |
Research interests
- Control of drug distribution for targeting to the desired region
- Development of new drug therapy to reduce side-effect
- Research on drug delivery system to develope new drug administration route
- Research on developement of distribution control and new formulation for gene medicine to optimize therapy
Selected publications
- Kodama Y, Horishita M, Tokunaga A, Miyamoto H, Fumoto S, Sasaki H, Nakamura J, Nishida K. Influence of vasomodulators and tumor transplantation on the disposition of 5-fluorouracil after application to the liver surface in rats. Biopharm Drug Dispos. 38(6):367-372 (2017). doi: 10.1002/bdd.2073. PMID: 28239866
- Wang S, Fumoto S, Miyamoto H, Tanaka M, Nishida K. Edaravone, a cytoprotective drug, enhances transgene expression mediated by lipoplexes in HepG2 cells and mice. Int J Pharm. 548(1):173-181 (2018). doi: 10.1016/j.ijpharm.2018.06.068. PMID: 29969708
- Peng JQ, Fumoto S, Suga T, Miyamoto H, Kuroda N, Kawakami S, Nishida K. Targeted co-delivery of protein and drug to a tumor in vivo by sophisticated RGD-modified lipid-calcium carbonate nanoparticles. J Control Release. 302:42-53 (2019). doi: 10.1016/j.jconrel.2019.03.021. PMID: 30926479
- Taniguchi M, Miyamoto H, Tokunaga A, Fumoto S, Tanaka T, Nishida K. Evaluation of mRNA expression of drug-metabolizing enzymes in acetaminophen-induced hepatotoxicity using a three-dimensional hepatocyte culture system. Xenobiotica. 50(6):654-662 (2020). doi: 10.1080/00498254.2019.1683258. PMID: 31631733
- Fumoto S, Kinoshita E, Ohta K, Nakamura KI, Hirayama T, Nagasawa H, Hu D, Okami K, Kato R, Shimokawa S, Ohira N, Nishimura K, Miyamoto H, Tanaka T, Kawakami S, Nishida K. A pH-Adjustable Tissue Clearing Solution That Preserves Lipid Ultrastructures: Suitable Tissue Clearing Method for DDS Evaluation. Pharmaceutics. 12(11):1070 (2020). doi: 10.3390/pharmaceutics12111070. PMID: 33182398; PMCID: PMC7698078
Works
Please find latest works in their website.
