Research

Cell Regulation
Division of Cell Regulation
Department of Cell Regulation
Course of Pharmaceutical Sciences
http://www.ph.nagasaki-u.ac.jp/lab/cell/index-e.html
Teaching Staff
Name Position E-mail Tel Fax
Kohsuke Takeda, DDS, Ph. D.
Professor
takeda-k@nagasaki-u.ac.jp +81-95-819-2417 +81-95-819-2472
Susumu Tanimura, Ph. D.
Associate Professor
tani1211@nagasaki-u.ac.jp +81-95-819-2419 +81-95-819-2472
Tomo Yonezawa, Ph. D.
Associate Professor
yonet@nagasaki-u.ac.jp +81-95-819-8525
Research
  • Mechanisms of mitochondrial sensing and stress response
  • Mitochondrial functions in the regulation of inflammation
  • Mechanisms of inflammatory death of macrophage lineage cells
  • Molecular mechanisms of cell motility
Selected Publications
  1. Honda S, Sadatomi D, Yamamura Y, Nakashioya K, Tanimura S, Takeda K, WP1066 suppresses macrophage cell death induced by inflammasome agonists independently of its inhibitory effect on STAT3, Cancer Sci. 108: 520-527 (2017)
  2. Sadatomi D, Nakashioya K, Mamiya S, Honda S, Kameyama Y, Yamamura Y, Tanimura S, Takeda K, Mitochondrial function is required for extracellular ATP-induced NLRP3 inflammasome activation, J. Biochem. 161: 503-512 (2017)
  3. Tanimura S, Hashizume J, Arichika N, Watanabe K, Ohyama K, Takeda K, Kohno M, ERK signaling promotes cell motility by inducing the localization of myosin 1E to lamellipodial tips, J. Cell Biol. 214: 475-489 (2016)
  4. Furuoka M, Ozaki K, Sadatomi D, Mamiya S, Yonezawa T, Tanimura S, Takeda K, TNF-α induces caspase-1 activation independently of simultaneously induced NLRP3 in 3T3-L1 cells, J. Cell. Physiol. 231: 2761-2727 (2016)
  5. Sadatomi D, Tanimura S, Ozaki K, Takeda K, Atypical protein phosphatases: emerging players in cellular signaling, Int. J. Mol. Sci. 14: 4596-4612 (2013) (Review article)
Research Paper List