Research

Pharmacology and Therapeutic Innovation
Pharmacology and Therapeutic Innovation
Department of
Pharmacology and Therapeutic Innovation
Course of Pharmaceutical Sciences
http://www.ph.nagasaki-u.ac.jp/lab/soyakuri/index-e.html
Teaching Staff
Name Position E-mail Tel Fax
Hiroshi UEDA, Ph. D.
Professor
ueda@nagasaki-u.ac.jp +81-95-819-2421 +81-95-819-2420
Tamotsu TSUKAHARA, Ph. D.
Associate Professor
ttamotsu@nagasaki-u.ac.jp +81-95-819-2473 +81-95-819-2420
Research
  • Chronic pain and LPA or epigenetic regulation
  • Beneficial DAMPs molecule
  • Kyotorphin and opioid research
  • Drug discovery against radiation damages
Selected Publications
  1. Inoue M, Rashid MH, Fujita R, Contos JJ, Chun J, Ueda H, Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling, Nat. Med. 10: 712-718 (2004)
  2. Ueda H, Fujita R, Yoshida A, Matsunaga H, Ueda M, Identification of prothymosin-α1, the necrosis-apoptosis switch molecule in cortical neuronal cultures, J. Cell Biol. 176: 853-862 (2007)
  3. Uchida H, Ma L, Ueda H, Epigenetic gene silencing underlies C-fiber dysfunctions in neuropathic pain, J. Neurosci. 30: 4608-4814 (2010)
  4. Omotuyi OI, Nagai J, Ueda H, Lys39-Lysophosphatidate carbonyl oxygen interaction locks LPA1 N-terminal cap to the orthosteric site and partners Arg124 during receptor activation.Sci. Rep. 5: 13343 (2015)
Research Paper List