Research

Analytical Chemistry for Pharmaceuticals
Analytical Chemistry for Pharmaceuticals
Department of Analytical Chemistry for Pharmaceuticals
Course of Pharmaceutical Sciences
http://www.ph.nagasaki-u.ac.jp/lab/analysis/index-e.html
Teaching Staff
Name Position E-mail Tel Fax
Naotaka Kuroda, Ph. D.
Professor
n-kuro@nagasaki-u.ac.jp

Naoya Kishikawa, Ph. D.
Associate Professor
kishika@nagasaki-u.ac.jp

Research
  • Development of sensitive analytical method for trace levels of biological substances and drugs and their application to clinical chemistry.
  • Development of organic reagent for luminescence analysis.
  • Development of comprehensive analytical method for immune complexes based on LC-MS/MS.
  • Development of novel silica gel column packing materials for HPLC and CEC.
  • Development and application of specific detection for reactive oxygen species.
Selected Publications
    1. Kishikawa N, Yamanouchi A, El-Maghrabey MH, Ohyama K, Kuroda N: Determination of tanshinones in Danshen (Salvia miltiorrhiza) by high-performance liquid chromatography with fluorescence detection after pre-column derivatization. Phytochemical Analysis 29(1): 112-117, 2018.
    2. Fukuda M, El-Maghrabey MH, Kishikawa N, Ikemoto K, Kuroda N: Ultrasensitive determination of pyrroloquinoline quinone in human plasma by HPLC with chemiluminescence detection using the redox cycle of quinone. Journal of Pharmaceutical and Biomedical Analysis 145: 814-820, 2017.
    3. Elgawish MS, Kishikawa N, Kuroda N: Redox-based chemiluminescence assay of aminothiols in human urine: A fundamental study. Talanta 164: 116-120, 2017.
    4. El-Maghrabey MH, Kishikawa N, Kuroda N: 9,10-Phenanthrenequinone as a mass-tagging reagent for ultra-sensitive liquid chromatography–tandem mass spectrometry assay of aliphatic aldehydes in human serum. Journal of Chromatography A 1462: 80-89, 2016.
    5. Yamada Y, Ohyama K, Onodera G, Kuriyama M, Kishikawa N, Kuroda N, Molecular-shape selectivity by naphthalimido-modified silica stationary phases: Insight into the substituents effect of naphthalene on shape recognition and π-π interactions via electrostatic potential,Journal of Chromatography A 1425: 173-179, 2015.
    Research Paper List