Research

Synthetic Chemistry for Pharmaceuticals
Synthetic Chemistry for Pharmaceuticals
Department of Synthetic Chemistry for Pharmaceuticals
Course of Pharmaceutical Sciences
http://www.ph.nagasaki-u.ac.jp/lab/synchem/index-e.html
Teaching Staff
Name Position E-mail Tel Fax
Osamu Onomura, Ph. D.
Professor
onomura@nagasaki-u.ac.jp +81-95-819-2429 +81-95-819-2476
Masami Kuriyama, Ph. D.
Associate Professor
mkuriyam@nagasaki-u.ac.jp +81-95-819-2430 +81-95-819-2476
Kosuke Yamamoto, Ph. D.
Assistant Professor
kyamamoto@nagasaki-u.ac.jp +81-95-819-2431 +81-95-819-2476
Research
  • Selective molecular transformation of diols based on molecular recognition
  • Activation of silanes by organic molecule and its application to highly efficient molecular transformation
  • Highly efficient synthesis of nitrogen heterocycles
  • New synthetic method for fluorinated organic compounds
Selected Publications
  1. Minato D, Nagasue Y, Demizu Y, Onomura O: Effecient kinetic resolution of racemic-aminoaldehydes by oxidation with N-iodosuccinimide. Angew Chem Int Ed 47: 9458-9461, 2008
  2. Kirira PG, Kuriyama M, Onomura O: Electrochemical deallylation of α-allyl cyclic amines and synthesis of optically active quaternary cyclic amino acids. Chem Eur J 16: 3970-3982, 2010
  3. Kuriyama M, Matsuo S, Shinozawa M, Onomura O: Ether-imidazolium carbenes for Suzuki–Miyaura cross-coupling of heteroaryl chlorides with aryl/heteroarylboron reagents. Org Lett 15: 2716-2719, 2013
  4. William JM, Kuriyama M, Onomura O: Boronic acid-catalyzed selective oxidation of 1,2-diols to α-hydroxy ketones in water. Adv Synth Catal 356: 934-940, 2014
  5. Kuriyama M, Kujirada S, Tsukuda K, Onomura O: Nickel-catalyzed deoxygenative deuteration of aryl sulfamates. Adv Synth Catal 359: 1043-1048, 2017
Research Paper List