Research

Synthetic Chemistry for Pharmaceuticals
Synthetic Chemistry for Pharmaceuticals
Department of Synthetic Chemistry for Pharmaceuticals
Course of Pharmaceutical Sciences
http://www.ph.nagasaki-u.ac.jp/lab/synchem/index-e.html
Teaching Staff
Name Position E-mail Tel Fax
Osamu Onomura, Ph. D.
Professor
onomura@nagasaki-u.ac.jp +81-95-819-2429 +81-95-819-2476
Masami Kuriyama, Ph. D.
Associate Professor
mkuriyam@nagasaki-u.ac.jp +81-95-819-2430 +81-95-819-2476
Kosuke Yamamoto, Ph. D.
Assistant Professor
kyamamoto@nagasaki-u.ac.jp +81-95-819-2431 +81-95-819-2476
Research
  • Selective molecular transformation of diols based on molecular recognition
  • Activation of silanes by organic molecule and its application to highly efficient molecular transformation
  • Highly efficient synthesis of nitrogen heterocycles
  • Highly selective oxidation by utilizing novel nitroxyl radicals
  • New synthetic method for fluorinated organic compounds
Selected Publications
  1. Minato D, Onomura O et al, Effecient kinetic resolution of racemic-aminoaldehydes by oxidation with NIS, Angew. Chem. Int. Ed. 47: 9458-9461 (2008)
  2. Kirira P. G, Onomura O et al, Electrochemical deallylation of α-allyl cyclic amines and synthesis of optically active quaternary cyclic amino acids, Chem. Eur. J. 16: 3970-3982 (2010)
  3. Kuriyama M, Onomura O et al, Copper (II)-catalyzed monoarylation of vicinal diols with diaryliodonium salts, Chem. Eur. J. 18: 1591-1594 (2012)
  4. Kuriyama M, Onomura O et al, Ether-imidazolium carbenes for Suzuki-Miyaura cross-coupling of heteroaryl chlorides with aryl/heteroarylboron reagents, Org. Lett. 15: 2716-2719 (2013)
  5. William J M., Onomura O et al, Boronic acid catalyzed selective oxidation of 1,2-diols to α-hydroxyketones in water, Adv. Synth. Cat. 356: 934-940 (2014)
Research Paper List