Research

Hygienic Chemistry
Hygienic Chemistry
Department of Hygienic Chemistry
Course of Pharmaceutical Sciences
http://www.ph.nagasaki-u.ac.jp/lab/hygiene/index-e.html
Teaching Staff
Name Position E-mail Tel Fax
Morio Nakayama, Ph. D.
Professor
morio@nagasaki-u.ac.jp
Takeshi Fuchigami, Ph. D.
Associate Professor
t-fuchi@nagasaki-u.ac.jp
Sakura Yoshida, Ph. D.
Assistant Professor
yoshida-s@nagasaki-u.ac.jp
Research
  • Analysis of marine organisms as a source of trace essential metals
  • Clarification of selenium metabolic pathways within living organisms
  • Development of nanosize particles with glutathione peroxidase-like activity
  • Development and clinical application of new 68Ge/68Ga generator
  • In vivo imaging of pathological elements resulting from amyloid deposition
  • Development of molecular probes for early diagnosis of cancer
Selected Publications
  1. Haratake M, Tachibana Y, Emaya Y, Yoshida S, Fuchigami T, Nakayama M, Synthesis of nanovesicular glutathione peroxidase mimics with a selenenylsulfide-bearing lipid, ACS Omega 1: 58-65 (2016)
  2. Fuchigami T, Yamashita Y, Kawasaki M, Ogawa A, Haratake M, Atarashi R, Sano K, Nakagaki T, Ubagai K, Ono M, Yoshida S, Nishida N, Nakayama M, Characterisation of radioiodinated flavonoid derivatives for SPECT imaging of cerebral prion deposits, Sci. Rep. 5: 18440 (2015)
  3. Hori E, Yoshida S, Haratake M, Ura S, Fuchigami T, Nakayama M, An effective method for profiling the selenium-binding proteins using its reactive metabolic intermediate, J. Biol. Inorg. Chem. 20: 781-789 (2015)
  4. Haratake M, Yoshida S, Mandai M, Fuchigami T, Nakayama M, Elevated amyloid-β plaque deposition in dietary selenium-deficient Tg2576 transgenic mice, Metallomics 2013: 479-483 (2013)
  5. Hongoh M, Haratake M, Fuchigami T, Nakayama M, A thiol-mediated active membrane transport of selenium by erythroid anionexchanger 1 protein, Dalton Trans. 41: 7340-7349 (2012)
Research Paper List