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Nagasaki University Graduate School of Biomedical Sciences
 
Research
 
HOME>Research>Hygienic Chemistry and Toxicology


Outline
Division of Hygienic Chemistry and Toxicology
Course of Pharmaceutical Sciences
Department of Environmental and Pharmaceutical Sciences
Details  Web Site
http://www.ph.nagasaki-u.ac.jp/lab/hygiene/index-e.html

Teaching Staff
Name Position E-mail Tel Fax
Morio Nakayama, Ph. D.
Professor
morio@nagasaki-u.ac.jp +81-95-819-2441 +81-95-819-2893
Mamoru Haratake, Ph .D.
Associate Professor
haratake@nagasaki-u.ac.jp +81-95-819-2442 +81-95-819-2893
Takeshi Fuchigami, Ph .D.
Assistant Professor
t-fuchi@nagasaki-u.ac.jp +81-95-819-2443 +81-95-819-2893

Research
  • An assessment of Niboshi (a processed Japanese anchovy) as an effective food source of selenium
  • Selenium metabolic pathways in biological systems
  • Blood glucose-lowering efficacy of vanadium (IV, V)-hydroxamate complexes in diabetic mellitus
  • In vivo Ab-aggregate imaging agents for early diagnosis of Alzheimer's disease
  • Development of a generator system for PET imaging agents not using cyclotron facility

Research Papers
  1. M. Ono et al, Radioiodinated flavones for in vivo imaging of É¿-amyloid plaques in the brain. J. Med. Chem., 48, 7253-7260 (2005).
  2. M. Haratake et al., Synthesis of vanadium(IV,V) hydroxamic acid complexes and in vivo assessment of their insulin-like activity, J. Biol. Inorg. Chem., 10, 250-258 (2005).
  3. M. Haratake et al, Selenium binding to human hemoglobin via selenotrisulfide, Biochim. Biophys. Acta., 1723, 215-220 (2005).
  4. M. Ono et al, Novel benzofuran derivatives for PET imaging of _-amyloid plaques in Alzheimer's disease brains, J. Med. Chem. 49, 2725-2730 (2006)
  5. M. Haratake, K. Yasumoto, M. Ono, M. Akashi and M. Nakayama: Synthesis of hydrophilic macroporous chelating polymers and their versatility in the preconcentration of metals in seawater samples, Anal. Chim. Acta, 561, 183-190 (2006)
   
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