Research

Pharmaceutical Informatics
Analytical Reseach for Pharmacoinformatics
Division of Pharmaceutical Informatics
Course of Medical and Dental Sciences
http://www.ph.nagasaki-u.ac.jp/lab/arp/index-e.html
Teaching Staff
Name Position E-mail Tel Fax
Shigeru Kawakami, Ph. D.
Professor
 skawakam@nagasaki-u.ac.jp +81-95-819-8563
Masayori Hagimori, Ph. D.
Associate Professor
 hagimori@nagasaki-u.ac.jp +81-95-819-8564
Research
  • Development of targeted gene delivery system using external stimuli
  • Development of functional liposomes for cell-selective targeting
  • Development of gene and nucleic acids delivery system
  • Development of nano-biotechnology for medical use
  • Evaluation of pharmaceutical information for proper use
Selected Publications
  1. Ogawa K, Fuchigami Y, Hagimori M, Fumoto S, Miura Y, Kawakami S: Efficient gene transfection of the brain with ultrasound irradiation in mice using stabilized bubble lipopolyplexes prepared by the surface charge regulation method, Int J Nanomed 13: 2309-2320, 2018
  2. Oyama N, Fuchigami Y, Fumoto S, Sato M, Hagimori M, Shimizu K, Kawakami S: Characterization of transgene expression and pDNA distribution of the suctioned kidney in mice. Drug Delivery 24(1): 906-917, 2017
  3. Nishimura K, Fumoto S, Fuchigami Y, Hagimori M, Maruyama K, Kawakami S: Effective intraperitoneal gene transfection system using nanobubbles and ultrasound irradiation. Drug Delivery 24(1): 737-744, 2017
  4. Suga T, Fuchigami Y, Hagimori M, Kawakami S: Ligand peptide grafted PEGylated liposomes using HER2 targeted peptide-lipid derivatives for targeted delivery in breast cancer cells: the effect of serine-glycine repeated peptides as a spacer. Int J Pharm 521(1-2): 361-364, 2017
  5. Fumoto S, Nishimura K, Nishida K, Kawakami S: Three-dimensional imaging of the intracellular fate of plasmid DNA and transgene expression: ZsGreen1 and tissue clearing method CUBIC are an optimal combination for multicolor deep imaging in murine tissues. PLoS One 11(1): e0148233, 2016
Research Paper List