Research

Pharmaceutical Informatics
Analytical Reseach for Pharmacoinformatics
Division of Pharmaceutical Informatics
Course of Medical and Dental Sciences
http://www.ph.nagasaki-u.ac.jp/lab/arp/index-e.html
Teaching Staff
Name Position E-mail Tel Fax
Shigeru Kawakami, Ph. D.
Professor
 skawakam@nagasaki-u.ac.jp +81-95-819-8563
Masayori Hagimori, Ph. D.
Associate Professor
 hagimori@nagasaki-u.ac.jp +81-95-819-8564
Yuki Fuchigami, Ph. D.
Assistant Professor
y-fuchigami@nagasaki-u.ac.jp +81-95-819-8578
Research
  • Development of targeted gene delivery system using external stimuli
  • Development of functional liposomes for cell-selective targeting
  • Development of nanobiotechnology for medical use
  • Evaluation of pharmaceutical information for proper use
Selected Publications
  1. Kurosaki T, Kawakami S, et al., Development of anionic bubble lipopolyplexes for efficient and safe gene transfection with ultrasound exposure in mice, Journal of Controlled Release, 176, 24-34 (2014)
  2. Fuchigami Y, et al., Warning against co-administration of 3,4-methylenedioxymethamphetamine (MDMA) with methamphetamine from the perspective of pharmacokinetic and pharmacodynamic evaluations in rat brain. Eur J Pharm Sci 49: 57-64  (2013)
  3. Un K, Kawakami S et al., Efficient suppression of ICAM-1 using ultrasound-responsive and mannose-modified lipoplexes inhibits acute hepatic inflammation, Hepatology, 56: 256-269 (2012)
  4. Un K, Kawakami S et al., Involvement of activated transcriptional process in the efficient gene transfection using unmodified and mannose-modified bubble lipoplexes with ultrasound exposure, J Control Release. 156: 355-363 (2011)
  5. Wijagkanalan W, Kawakami S, et al.,  Intratracheally instilled mannosylated cationic liposome/NFκB decoy complexes for effective prevention of LPS-induced lung inflammation, Journal of Controlled Release, 149 (1), 42-50 (2011)
Research Paper List