Research

Pharmaceutical Chemistry
Pharmaceutical Chemistry
Department of Pharmaceutical Chemistry
Course of Pharmaceutical Sciences
Web Site
Teaching Staff
Name Position E-mail Tel Fax
Masakazu Tanaka Ph. D.
Professor
matanaka@nagasaki-u.ac.jp +81-95-819-2423 +81-95-819-2423
Makoto Oba Ph. D.
Associate Professor
moba@nagasaki-u.ac.jp +81-95-819-2424 +81-95-819-2423
Atsushi Ueda Ph. D.
Assistant Professor
aueda@nagasaki-u.ac.jp +81-95-819-2425 +81-95-819-2423
Research
  • Synthesis of non-natural type amino acids and its application to medicinal chemistry
  • Development of helical peptides as an asymmetric organocatalyst
  • Design of cell-penetrating foldamers and their application to drug delivery system
Selected Publications
  1. Ueda A, Umeno T, Doi M, Akagawa K, Kudo K, Tanaka M, Helical peptide-catalyzed enantioselective Michael addition reactions and their mechanistic insights, J. Org. Chem. 81: 6343-6356 (2016)
  2. Oba M, Kato T, Furukawa K, Tanaka M, A cell-penetrating peptide with a guanidinylethyl amine structure directed to gene delivery, Sci. Rep. 6: 19913 (2016)
  3. Yamashita H, Oba M, Misawa T, Tanaka M, Hattori T, Naito M, Kurihara M, Demizu Y, A helix-stabilized cell-penetrating peptide as an intracellular-delivery tool, ChemBioChem 17: 137-140 (2016) (Cover picture)
  4. Oba M, Takazaki H, Kawabe N, Doi M, Demizu Y, Kurihara M, Kawakubo H, Nagano M, Suemune H, Tanaka M, Helical peptide-foldamers having a chiral five-membered ring amino acid with two azido functional groups, J. Org. Chem. 79: 9125-9140 (2014)
  5. Kato T, Oba M, Nishida K, Tanaka M, Cell-penetrating helical peptides having L-arginines and five-membered ring α,α-disubstituted α-amino acids, Bioconjugate Chem. 25: 1761-1768 (2014)
Research Paper List