Research
Department of Pharmacy Practice
Course of Medical and Dental Sciences
http://www.ph.nagasaki-u.ac.jp/lab/hospital/index-e.html
Teaching staffs
| Name, Position | Email *convert [a] to @ |
Tel | Fax |
|---|---|---|---|
| Mikiro Nakashima, Ph. D. Professor | mikirou[a]nagasaki-u.ac.jp | +81-95-819-8570 | +81-95-819-8572 |
| Nozomi Aibara, Ph. D. Assistant Professor | nozomi-ai[a]nagasaki-u.ac.jp | +81-95-819-8569 |
|
| Yuki Kutsuna Assistant Professor |
jim_kutsuna[a]nagasaki-u.ac.jp | +81-95-819-8569 |
Research interests
- Propose use of PXB-mice® as a reliable tool for drug repositioning screening against liver disease
- Screening disease-specific immune complex antigens for autoimmune diseases and cancers
- Measure the concentration of drugs binding to their target
Selected publications
- Kutsuna YJ, Aibara N, Hashizume J, Omori W, Okada TM, Kajitani N, Nakashima M, Kawakami A, Ohyama K, Takebayashi M, Identification of shared pathophysiological molecules of major psychiatric disorders: A comprehensive analysis of serum immune complex antigens before and after electroconvulsive therapy, Journal of Neuroimmunology,405: 57862, 2025
- Moriishi M, Takazono T, Hashizume J, Aibara N, Kutsuna YJ, Okamoto M, Sawai T, Hoshino T, Mori Y, Fukuda Y, Awaya Y, Yamanashi H, Furusato Y, Yanagihara T, Miyamoto H, Sato K, Kodama Y, Mizukami S, Sakamoto N, Yamamoto K, Sakamoto K, Yanagihara K, Izumikawa K, Maeda T, Nakashima M, Fukushima K, Mukae H, Ohyama K: Immune complexome analysis reveals an autoimmune signature predictive of COVID-19 severity, Clinical Biochemistry, 135:110865, 2025
- Kutsuna YJ, Iwamoto N, Ichinose K, Aibara N, Nakashima K, Nakamura H, Koike Y, Murota H, Ueki Y, Miyamoto H, Hashizume J, Kodama Y, Nakashima M, Kawakami A, Ohyama K, Immune complexome analysis of a rich variety of serum immune complexes identifies disease-characteristic immune complex antigens in systemic sclerosis, Journal of Autoimmunity, 134:102954, 2023
- Aizawa R, Nakamura Y, Ikeda T, Aibara N, Kutsuna YJ, Kurosaki T, Aki K, Hashizume J, Nakagawa H, Sato K, Kodama Y, Nakashima MN, Nakashima M, Mukae H, Ohyama K: Immune complexome analysis of serum samples from non-small-cell lung cancer patients identifies predictive biomarkers for nivolumab therapy, Clinica Chimica Acta, 532:84-88, 2022
- Aibara N, Ohyama K, Nakamura M, Nakamura H, Tamai M, Kishikawa N, Kawakami A, Tsukamoto K, Nakashima M, Kuroda N: Investigation of immune complexes formed by mitochondrial antigens containing a new lipoylated site in sera of primary biliary cholangitis patients. Clinical & Experimental Immunology, 204:335-343, 2021
Works
Please find latest works in their website.
