Department of Pharmaceutical Chemistry

Analytical Chemistry for Pharmaceuticals

Course of Pharmaceutical Sciences

Teaching staffs

Name, Position Email
*convert [a] to @
Tel Fax
Masakazu Tanaka, Ph. D. Professor matanaka[a] +81-95-819-2423 +81-95-819-2423
Atsushi Ueda, Ph. D. Associate Professor aueda[a] +81-95-819-2425 +81-95-819-2423

Research interests

  • Synthesis of non-natural type amino acids and its application to medicinal chemistry
  • Development of helical peptides as an asymmetric organocatalyst
  • Design of cell-penetrating foldamers and their application to drug delivery system

Selected publications

  • Ueda A, Makura Y, Kakazu S, Kato T, Umeno T, Hirayama K, Doi M, Oba M, Tanaka M: E-Selective ring-closing metathesis in α-helical stapled peptides using carbocyclic α,α-disubstituted α-amino acids. Org Lett 24: 1049-1054, 2022
  • Sato K, Umeno T, Ueda A, Kato T, Doi M, Tanaka M: Asymmetric 1,4-addition reactions catalyzed by N-terminal thiourea-modified helical L-Leu-peptide with cyclic amino acids. Chem-Eur J 27: 11216-11220, 2021
  • Yamaberi Y, Eto R, Umeno T, Kato T, Doi M, Yokoo H, Oba M, Tanaka M: Synthesis of (S)-(-)-Cucurbitine and Conformation of Its Homopeptides. Org Lett 23: 4358-4362, 2021
  • Uchida S, Yamaberi Y, Tanaka M, Oba M: A helix foldamer oligopeptide improves intracellular stability and prolongs protein expression of delivered mRNA. Nanoscale 13: 18941, 2021
  • Furukawa K, Tanaka M, Oba M: siRNA delivery using amphipathic cell-penetrating peptides into human hepatoma cells. Bioorg Med Chem 28: 115402, 2020


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