Research

Laboratory in Medical Plants Garden

Analytical Chemistry for Pharmaceuticals

Course of Pharmaceutical Sciences


Teaching staffs

Name, Position Email
*convert [a] to @
Tel Fax
Koyo Nishida, Ph. D. Professor
koyo-n[a]nagasaki-u.ac.jp +81-95-819-8566  +81-95-819-8566 
Koji Yamada, Ph. D. Associate Professor kyamada[a]nagasaki-u.ac.jp +81-95-819-2462  +81-95-819-2462 

Research interests

  • Studies on differentiation and substance production of plant tissue.
  • Studies on breeding and strain preservation of medicinal plants and functions of secondary metabolites
  • Chemo-pharmaceutical studies on biologicaqll active components derived from African medicinal plants.
  • Chemo-pharmaceutical studies on marine microbial products and bioactive components derived from marine invertebrates.
  • Construction of an extract library derived from natural resources as a drug discovery resource.

Selected publications

  • Riho Kurata , Kenji Shimizu, Xiaofeng Cui, Masamitsu Harada, Takayuki Isagawa, Hiroaki Semba,Jun Ishihara, Koji Yamada, Jun Nagai, Yasuhiro Yoshida, Norihiko Takeda, Koji, Maemura,Tomo Yonezawa: Novel Reporter SystemMonitoring IL-18 Specific Signaling Can Be Applied toHigh-Throughput Screening, Marine drugs, 18(2020), 60–71, 2020.
  • Nagat Ghareba, Norhan M. El-Sayedc, Reda Abdelhameedd, Yamada K, Mohamed Saleh Elgawishe: Toward a treatment of diabesity: Rational design, synthesis and biological evaluation of benzene-sulfonamide derivatives as a new class of PTP-1B inhibitors, Bioorganic Chemistry 86 (2019) 322–338, 2019.
  • Reda F. A. Abdelhameed, Sameh S. Elhady, Ahmad O. Noor, Diena M. Almasri, Alaa A. Bagalagel, Galal T. Maatooq, Amgad I. M. Khedr and Yamada K: Production of a New Cyclic Depsipeptide by the Culture Broth of Staphylococcus sp. Isolated from Corallina ocinalis L., Metabolites, 2019, 9, 273–281, 2019.
  • Mohamed S. Refaey, Reda A. Abdelhamid, Mohamed A. A. Orabi, Ahmmed A. Ali, Reda Fouad Ahmed Abdelhameed, Eman A. A. Mousa, Shinjiro Hamano, and Yamada K: Anew Iridodi Glucoside from Anisacanthus virgularis and Its Antiamoebic Activity, Heterocycles, 98 (9), 1229–1235, 2019.
  • Rania El-Shaheny, Mohamed Radwan, Yamada K and Mahmoud El-Maghrabey: Estimation of nizatidine gastric nitrosatability andproduct toxicity via an integrated approachcombining HILIC, in silico toxicology, andmolecular docking, Journal of Food and Drug Analysis, 27(4), 915–925, 2019.

Works

Please find latest works in their website.

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