Department of Pharmaceutical Informatics

Analytical Chemistry for Pharmaceuticals

Course of Medical and Dental Sciences

Teaching staffs

Name, Position Email
*convert [a] to @
Tel Fax
Shigeru Kawakami,
Ph. D., Professor
skawakam[a] +81-95-819-8563
Hidefumi Mukai, Ph.D., Associate Professor hmukai[a] +81-95-819-8564
Kohta Mohri, Ph.D., Associate Professor k.mohri[a] +81-95-819-8579
Shota Warashina, Ph.D., Assistant Professor shota.warashina[a] +81-95-819-8579
Shoko Nomura, Ph.D., Assistant Professor shoko.nomura[a] +81-95-819-8579
Mariko Kamiya, Ph.D., Assistant Professor mkamiya[a] +81-95-819-8578

Research interests

  • Development of cell-selective targeting system using lipid nanoparticles
  • Development of drug delivery system for nucleic acid drugs targeting to the brain
  • Development of T cell-induced vaccine based on mRNA delivery
  • Development of functionalized extracellular vehicles using microfluidic method
  • Development of designer bacteria for the treatment of intractable cancer
  • Development of companion / precision diagnostics by PET

Selected publications

  • Geng L, Kato N, Kodama Y, Mukai H, Kawakami S: Influence of lipid composition of messenger RNA-loaded lipid nanoparticles on the protein expression via intratracheal administration in mice. Int J Pharm 637: 122896, 2023
  • Sugimoto Y, Suga T, Umino M, Yamayoshi A, Mukai H, Kawakami S: Investigation of enhanced intracellular delivery of nanomaterials modified with novel cell-penetrating zwitterionic peptide-lipid derivatives. Drug Delivery 30: 2191891, 2023
  • Kato N, Yamada S, Suzuki R, Iida Y, Matsumoto M, Fumoto S, Arima H, Mukai H, Kawakami S: Development of an apolipoprotein E mimetic peptide–lipid conjugate for efficient brain delivery of liposomes. Drug Delivery 30: 2173333, 2023
  • Kato N, Sato T, Fuchigami Y, Suga T, Geng L, Tsurumaru M, Hagimori M, Mukai H, Kawakami S: Synthesis and evaluation of a novel adapter lipid derivative for preparation of cyclic peptide-modified PEGylated liposomes: Application of cyclic RGD peptide. Eur J Pharm Sci 176: 106239, 2022
  • Ogawa K, Kato N, Yoshida M, Hiu T, Matsuo T, Mizukami S, Omata D, Suzuki R, Maruyama K, Mukai H, Kawakami S: Focused ultrasound/microbubbles-assisted BBB opening enhances LNP-mediated mRNA delivery to brain. J Controlled Release 348: 34-41, 2022


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