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2017年度にゲノム創薬学研究室のセミナー時に紹介された文献の一覧です。
ゲノム創薬学研究室のセミナーでは、インパクトファクター 7以上の雑誌の中から最近公表されたアルツハイマー病に関わる文献を紹介し、批判的な視点を養うと共に、新しい知見や技術を学び、プレゼンテーション能力や論理的な思考の向上に努めています。

・2018年度に紹介された文献一覧 
・2017年度に紹介された文献一覧 
・2016年度に紹介された文献一覧 
・2015年度に紹介された文献一覧 
・2014年度に紹介された文献一覧 
・2013年度に紹介された文献一覧 
・2012年度に紹介された文献一覧 

#14 (2019/06/7; by YH)

Zhang P, Kishimoto Y, Grammatikakis I, Gottimukkala K, Cutler RG, Zhang S, Abdelmohsen K, Bohr VA, Misra Sen J, Gorospe M, Mattson MP.
Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer's disease model.
Nat Neurosci 2019; 22(5):719-728
PMID: 30936558

#13 (2019/06/7; by KN)

Paonessa F, Evans LD, Solanki R, Larrieu D, Wray S, Hardy J, Jackson SP, Livesey FJ.
Microtubules deform the nuclear membrane and disrupt nucleocytoplasmic transport in tau-mediated frontotemporal dementia.
Cell Rep 2019;26(3):582-593.e5
PMID: 30650353

#12 (2019/05/23; by DH)

Yang Y, Tian X, Xu D, Zheng F, Lu X, Zhang Y, Ma Y, Li Y1, Xu X, Zhu B, Wang X.
GPR40 modulates epileptic seizure and NMDA receptor function.
Sci Adv 2018; 4(10): eaau2357
PMID: 30345361

#11 (2019/05/23; by YO)

Srivastava S, Katorcha E, Makarava N, Barrett JP, Loane DJ, Baskakov IV.
Inflammatory response of microglia to prions is controlled by sialylation of PrPSc.
Sci Rep 2018; 8(1):11326
PMID: 30054538

#10 (2019/05/10; by RO)

Kaneko N, Herranz-Pérez V, Otsuka T, Sano H, Ohno N, Omata T, Nguyen HB, Thai TQ, Nambu A, Kawaguchi Y, García-Verdugo JM, Sawamoto K.
New neurons use Slit-Robo signaling to migrate through the glial meshwork and approach a lesion for functional regeneration.
Sci Adv 2018; 4(12): eaav0618
PMID: 30547091

#09 (2019/04/26; by DH)

Awasthi A, Ramachandran B, Ahmed S, Benito E, Shinoda Y, Nitzan N, Heukamp A, Rannio S, Martens H, Barth J, Burk K, Wang YT, Fischer A, Dean C.
Synaptotagmin-3 drives AMPA receptor endocytosis, depression of synapse strength, and forgetting.
Science 2019; 363(6422)
PMID: 30545844

#08 (2019/04/26; by SY)

Losev Y, Paul A, Frenkel-Pinter M, Abu-Hussein M, Khalaila I, Gazit E, Segal D.
Novel model of secreted human tau protein reveals the impact of the abnormal N-glycosylation of tau on its aggregation propensity.
Sci Rep 2019;9(1):2254
PMID: 30783169

#07 (2019/04/19; by NW)

Ma Q, Zhao Z, Sagare AP, Wu Y, Wang M, Owens NC, Verghese PB, Herz J, Holtzman DM, Zlokovic BV.
Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism.
Mol. Neurodegener. 2018, 13: 57
PMID: 30340601

#06 (2019/04/19; by NK)

Baker SK, Chen ZL, Norris EH, Revenko AS, MacLeod AR, Strickland S.
Blood-derived plasminogen drives brain inflammation and plaque deposition in a mouse model of Alzheimer's disease
Proc Natl Acad Sci USA 2018: 115(41):E9687-E9696
PMID: 30254165

#05 (2019/04/12; by YT)

Fang EF, Hou Y, Palikaras K, Adriaanse BA, Kerr JS, Yang B, Lautrup S, Hasan-Olive MM, Caponio D, Dan X, Rocktäschel P, Croteau DL, Akbari M, Greig NH, Fladby T, Nilsen H, Cader MZ, Mattson MP, Tavernarakis N, Bohr VA.
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.
Nat Neurosci 2019; 22(3):401-412
PMID: 30742114

#04 (2019/04/12; by MT)

Mouchard A, Boutonnet MC, Mazzocco C, Biendon N, Macrez N; Neuro-CEB Neuropathology Network.
ApoE-fragment/Aβ heteromers in the brain of patients with Alzheimer's disease
Sci Rep 2019; 9(1):3989
PMID: 30850702

#03 (2019/04/5; by YH)

Sawangjit A, Oyanedel CN, Niethard N, Salazar C, Born J, Inostroza M.
The hippocampus is crucial for forming non-hippocampal long-term memory during sleep
Nature 2018;9(1):51
PMID: 30429612

#02 (2019/04/5; by KM)

Benjamin B. T, Stergios T, Daphney R, Christine F, Thomas C, Frédéric F, Tien P, Marie-Claude G, Eniko K, Marcelle MS, Armand S, Philippe M.
TSPO and amyloid deposits in sub-regions of the hippocampus in the 3xTgAD mouse model of Alzheimer's disease
Neurobiol Dis 2018; 564(7734):109-113
PMID: 30261283

#01 (2019/04/5; by CO)

Smith LM, Kostylev MA, Lee S, Strittmatter SM
Systematic and standardized comparison of reported Amyloid-β receptors for sufficiency, affinity, and Alzheimer's disease relevance
J Biol Chem 2019; 294(15):6042-6053
PMID: 30787106



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