118

• Construction of the Decalin Moiety of Pyrroindomycins
• Tomohiro Tsutsumi, Keita Komine, Hayato Fukuda, Jun Ishihara
• European Journal of Organic Chemistry, 2026, 29 e70450.
• 

117

• Total Syntheses of (+)-Penicibilaenes A and B via Enantioselective Desymmetrization 
• Taiga Iwanaga, Satoshi Kishimoto, Hayato Fukuda, Keita Komine, Jun Ishihara
• Organic Letters, 2026, 28 (4), 1452-1456.
• 

116

• Design and Synthesis of Cyclopropane Congeners of Resolvin E2 with Azidopropoxy Chain toward a Chemical Tool for Probing the Anti-inflammatory Activity.
• Hayato Fukuda、Kotaro Matsubara, Ayaka Hamaguchi, Hina Nishikoori, Mayu Shinohara, Jun Takouda, Kohsuke Takeda, Keijo Fukushima, Keita Komine, Koichi Fujiwara, Mizuki Watanabe, Jun Ishihara, Hiromichi Fujino, Satoshi Shuto
• The Journal of organic chemistry, 2026, 91 (1), 466-476 .
• 

115

• Lamellarin D Acts as an Inhibitor of Type I Collagen Production.
• Daisuke Okuno, Noriho Sakamoto, Hideki Hayashi, Tsutomu Fukuda, Yoshiko Akiyama, Chiaki Iketani, Ritsuko Murakami, Takatomo Tokito, Takuto Miyamura, Hirokazu Yura, Takashi Kido, Hiroshi Ishimoto, Shinnosuke Takemoto,  Takahiro Takazono,  Tomoya Nishino, Yuji Ishimatsu,  Jun Ishihara, Kohsuke Takeda, Yoshimasa Tanaka,  Hiroshi Mukae
• ChemMedChem, 2025, 20 , e20240100.

114

• Progress in Lewis-Acid-Templated Diels–Alder Reactions
• Jun ISHIHARA
• Molecules, 2024, 29 (5), 1187.
• 

113

• Identification of Azalamellarin N as a Pyroptosis Inhibitor
• Jun Takouda, Moeka Nakamura, Akane Murasaki, Waka Shimosako, Aoi Hidaka, Shino Honda, Susumu Tanimura, Fumito Ishibashi, Norihiko Kawasaki, Jun Ishihara, Tsutomu Fukuda, Kohsuke Takeda
• Biological and Pharmaceutical Bulletin , 2024, 47 (1), 28-36.

112

• Reaction Mechanism and Origin of Stereoselectivity in the Fluorination and Trifluoromethylthiolation of 2‐Bromoamides with AgF and AgSCF3
• Satoshi Mizuta, Masahiro Tabira, Naoki Shichiro,Tomoko Yamaguchi, Jun Ishihara, Takeshi Ishikawa
• Eur. J. Org. Chem. , 2024, 27 e202301100.

111

• Visible-Light-Induced Three-Component Radical Coupling of Selenocarbamates, Enones, and Allylstannanes with Diphenyl(2,4,6-trimethylbenzoyl)phosphine Oxide
• Keita KOMINE, Yuta YAMAZAKI, Taiga IWANAGA, Hikaru SAKAGUCHI, Hayato FUKUDA, Jun ISHIHARA
• Synlett, 2024, 35, 1279-1284.
• 

110

• Concise Formal Synthesis on Solandelactone E Based on a Regioselective Cyclopropanation
• Kawasaki, Norihiko; Kikuoka, Yu; Komine, Keita; Fukuda, Hayato; Ishihara, Jun
• HETEROCYCLES, 2023, 106 (2), 346-346.
• 

109

• Radical 4-exo cyclization of bicyclo[2.2.2]octene derivatives: Construction of tricyclo[3.3.1.02,7]nonane skeleton
• Komine, Keita; Kishimoto, Satoshi; Fukuda, Hayato; Ishihara, Jun
• Tetrahedron Letters, 2022, 105 154056-154056.
• 

108

• A Stereoselective Synthesis of Fused Carbocycles with a cis-1,2-Diols Moiety by Desymmetrization: SmI2-Mediated Pinacol Coupling of meso-Cyclic 1,3-Diones
• Komine, Keita; Ninomiya, Riki; Fukuda, Hayato; Ishihara, Jun
• Chem. Pharm. Bull., 2022, 70 (1), 89-93.
• 

107

• Trifluoromethylthiolation of Hindered a-Bromoalides with Nucleophilic Trifluoromethylthiolating Reagents
• Mizuta, Satoshi; Kitamura, Kanami; Morii, Yuki; Ishihara, Jun; Yamaguchi, Tomoko; Ishikawa, Takeshi
• Journal of Organic Chemistry, 2021, 86 (24), 18017-18029.
• 

106

• Screening of Inhibitors Targeting Heat Shock Protein 47 Involved in the Development of Idiopathic Pulmonary Fibrosis
• Okuno, Daisuke; Sakamoto, Noriho; Tagod, S. O. Mohammed; Akiyama, Yoshiko; Moriyama, Sakiko; Miyamura, Takuto; Hara, Atsuko; Kido, Takashi, Ishimoto, Hiroshi; Ishimatsu, Yuji; Tanaka, Takashi, Ishihara, Jun; Takeda, Kohsuke; Tanaka, Yoshimasa, Mukae, Hiroshi
• ChemMedChem, 2021, 16, 2515-2523.

105

• Total Synthesis of Thuggacin cmc-A and Its Structure Determination
• Tsutsumi, Tomohiro; Matsumoto, Moe; Iwasaki, Hitomi; Tomisawa, Kei; Komine, Keita; Fukuda, Hayato; Eustache, Jacques; Jansen, Rolf; Hatakeyama, Susumi; Ishihara, Jun
• Organic Letters, 2021, 23 (13), 5208-5212.
• 

104

• Synthesis of Resolvin E1 and Its Conformationally Restricted Cyclopropane Congeners with Potent Anti-Inflammatory Effect
• Ishimura, Kohei; Fukuda, Hayato; Fujiwara, Koichi; Muromoto, Ryuta; Hirashima; Koki; Murakami, Yuto; Watanabe, Mizuki; Ishihara, Jun; Matsuda, Tadashi; Shuto, Satoshi
• ACS Medicinal Chemistry Letters, 2021, 12 (2), 256-261.
• 

103

• Catalytic Asymmetric Total Synthesis of Exiguolide
• Oka, Kengo; Fuchi Shunsuke; Komine, Keita; Fukuda, Hayato; Hatakeyama, Susumi; Ishihara, Jun
• Chemistry - A European Journal, 2020, 25 (26), 12862-12867.
• 

102

• Formal Synthesis of (-)-Haliclonin A: Stereoselective Construction of an Azabicylco[3.3.1]nonane Ring System by a Tandem Radical Reaction
• Komine, Keita; Urayama, Yasuhiro; Hosaka, Taku; Yamashita, Yuki; Fukuda, Hayato; Hatakeyama, Susumi; Ishihara, Jun
• Organic Letters, 2020, 22 (13), 5046-5050.
• 

101

• Synthsis of Resolvin E3, a Proresolving Lipid Mediator, and Its Deoxy Derivatives: Identification of 18-Deoxy-resolvin E3 as a Potent Anti-Inflammatory Agent
• Fukuda, Hayato; Ikeda, Hiroyuki; Muromoto, Ryuta; Hirashima, Koki; Ishimura, Kohei; Fujiwara, Koichi; Aoki-Saito, Haruka, Hisada, Takeshi; Watanabe, Mizuki; Ishihara, Jun; Matsuda, Tadashi; Shuto, Satoshi
• J. Org. Chem., 2020, 85 (21), 14190-14200.
• 

100

• Design and Synthesis of Benzene Congeners of Resolvin E2, a Prorelvin E2, a Proresolving, Lipid Mediator, as Its Stable Equivalents
• Murakami, Yuto; Fukuda, Hayato; Muromoto, Ryuta; Hirashima; Koki; Ishimura, Kohei; Fujiwara, Koichi; Ishihara, Jun; Matsuda, Tadashi; Watanabe, Mizuki; Shuto, Satoshi
• ACS Medicinal Chemistry Letters, 2020, 11 (4), 479-484.
• 

99

• New entry to the enantioselective formation of substituted cyclohexenes bearing an all-carbon quaternary stereogenic center
• Komine, Keita; Urayama, Yasuhiro; Hosaka, Taku; Fukuda, Hayato; Hatakeyama, Susumi; Ishihara, Jun
• Chirality, 2020, 32 (3), 273-281.
• 

98

• Concise Synthesis of TPCA-1 and Related Thiophene Carboxamides by Cross Coupling
• Kawasaki, Norihiko; Fukuda, Hayato; Ishihara, Jun
• Heterocycles, 2020, 101 (2), 707-716.
• 

97

• Synthetic Studies on Marineosins Based on a Direct Coupling Reactions of Pyrrole and δ-Lactone
• Yamamoto, Kohei; Morii, Yuki; Suga, Akihisa; Komine, Keita; Fukuda Hayato; Ishihara, Jun
• Heterocycles, 2020, 100 (1), 46-59.
• 

総説

• キラル Lewis 酸テンプレートを用いる不斉Diels-Alder反応と天然物合成への応用
• 石原　淳
• 有機合成化学協会誌, 2020, 78 (3), 204-212.
• 

96

• Total Synthesis of Lajollamycin B
• Nishimaru, Tatsuya; Eto, Kohei; Komine, Keita; Ishihara, Jun; Hatakeyama, Susumi
• Chemistry - A European Journal, 2019, 25 (33), 77927-7934.
• 

95

• Bimetallic Lewis Acid Template-Mediated Enantioselective Hetero-Diels-Alder Reactions of 4-Siloxy-2,4-pentadienols
• Ishihara, Jun; Ohzono, Yuka, Oka, Kengo, Urayama, Yasuhiro, Hatakeyama, Susumi
• Heterocycles, 2019, 99 (2), 1330-1341.
• 

94

• Synthetic Studies on Spirolides A and B: Formation of the Upper Carbon Framework Based on a Lewis Acid Template‐Catalyzed Diels‐Alder Reaction
• Ishihara, Jun; Usui, Fuma; Kurose, Tomohiro; Baba, Tomohiro; Kawaguchi,
• Yasunori; Watanabe, Yuki; Hatakeyama, Susumi
• Chemistry - A European Journal, 2019, 25 (6), 1543-1552.
• 

93

• Synthetic Study of Thermolides: Stereoselective Construction of the C10-C21 Fragment.
• Yoshimura, Hikaru; Ishihara, Jun; Hatakeyama, Susumi.
• Heterocycles, 2018, 97 (2), 702-707.
• 

92

• Stereoselective Synthesis of the Right-hand Cores of 16-Methylated Oxazolomycins.
• Eto, Kohei; Ishihara, Jun; Hatakeyama, Susumi.
• Tetrahedron, 2018, 74 (7), 711-719.
• 

91

• Stereoselective Construction of Entire Diastereomeric Stereotetrads Based on an AsymmetricMorita–Baylis–Hillman Reaction.
• Yoshimura, Hikaru; Ishihara, Jun; Hatakeyama, Susumi.
• Eur. J. Org. Chem., 2017, 19, 2719–2729.
• 

90

• Ionic Liquid-Mediated Hydrofluorination of o-Azaxylylenes Derived from 3-Bromooxindoles.
• Mizuta, Satoshi; Otaki, Hiroki; Kitagawa, Ayako; Kitamura, Kanami; Morii, Yuki; Ishihara, Jun; Nishi, Kodai; Hashimoto, Ryo; Usui, Toshiya; Chiba, Kenya.
• Org. Lett., 2017, 19 (10), 2572–2575.
• 

89

• Concise Formation of Spirocyclic Compounds for Marine Phycotoxins.
• Ishihara, Jun; Tojo, Shingo; Makino, Takuya; Sekiya, Hiroshi; Tanabe, Akiko, Shiraishi, Mitsutaka, Murai, Akio; Hatakeyama, Susumi.
• Heterocycles, 2017, 95 (1), 422-444.
• 

88

• Enantioselective Protecting-Group-Free Synthesis of (+)-9,10-Dihydroecklonialactone B.
• Yassen, Asmaa Said Ali; Ishihara, Jun; Hatakeyama, Susumi.
• Heterocycles, 2017, 94 (1), 59-63.
• 

87

• Unified Synthesis of Tirandamycins and Streptolydigins.
• Yoshimura, Hikaru; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi.
• Chemical Communications, 2015, (51), 17004–17007.
• 

86

• Total Synthesis of (−)-N-Methylwelwitindolinone C Isothiocyanate Based on a Pd-Catalyzed Tandem Enolate Coupling Strategy.
• Komine, Keita; Nomura, Yusuke; Ishihara, Jun; Hatakeyama, Susumi.
• Organic Letters, 2015, 17 (15), 3918–3921.
• 

85

• Lewis Acid Template-Catalyzed Asymmetric Diels-Alder Reaction.
• Ishihara, Jun; Nakadachi, Shino; Watanabe, Yuki; Hatakeyama, Susumi.
• Journal of Organic Chemistry, 2015, 80 (4), 2037-2041.
• 

84

• Stereoselective Approach toward Ophiodilactones Based on an Intramolecular [2+2] Cycloaddition Reaction.
• Matsubara, Takaaki; Ishihara, Jun; Hatakeyama, Susumi.
• Heterocycles, 2015, 90 (1), 405-424.
• 

83

• Total Synthesis of Marinomycin A Based on a Direct Dimerization Strategy.
• Nishimaru, Tatsuya; Kondo, Masashi; Takeshita, Kimito; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi.
• Angewandte Chemie, International Edition, 2014, 53, 8459-8462.
• 

82

• Total Synthesis of Oxazolomycins.
• Jun Ishihara; Susumi Hatakeyama.
• The Chemical Record, 2014, 14 (4), 663-677.
• 

81

• The Absolute Configuration for Inthomycin C: Revision of Previously Published Work with a Reinstatement of the (3R)-Configuration for (-)-Inthomycin C.
• Hale, Karl J.; Hatakeyama, Susumi; Urabe, Fumiya; Ishihara, Jun; Manaviazar, Soraya; Grabski, Milosz; Maczka, Maciej.
• Organic Letters, 2014, 16 (13), 3536-3539.
• 

80

• Total Synthesis of (-)-Dihydrosporothriolide Utilizing an Indium-Mediated Reformatsky-Claisen Rearrangement.
• Ishihara, Jun; Tsuru, Hiroaki; Hatakeyama, Susumi.
• Journal of Organic Chemistry, 2014, 79 (12), 5908-5913.
• 

79

• Formal [4+1]-Cycloaddition of homopropargyl alcohols to diazo dicarbonyl compounds giving substituted tetrahydrofurans.
• Urabe, Fumiya; Miyamoto, Shohei; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi.
• Organic Letters, 2014, 16 (3), 1004–1007.
• 

78

• Total Synthesis of (-)-Ophiodilactone A and (-)-Ophiodilactone B.
• Matsubara, Takaaki; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi.
• Angewandte Chemie - International Edition, 2014, 53 (3), 757–760.
• 

77

• Synthesis of Heterocycles Based on Rhodium-Catalyzed C-H Amination.
• Takahashi, Keisuke; Yamaguchi, Daisuke; Ishihara, Jun; Hatakeyama, Susumi.
• Synlett, 2014, 25 (1), 133–137.
• 

76

• α-Isocupreine, an enantiocomplementary catalyst of β-isocupreidine.
• Nakamoto, Yoshito; Urabe, Fumiya; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi
• Chemistry - A European Journal, 2013, 19 (38), 12653–12656.
• 

75

• Total synthesis of (-)-cinatrin C1 based on an In(OTf)3-catalyzed Conia-ene reaction
• Urabe, Fumiya; Nagashima, Shunsuke; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi
• Journal of Organic Chemistry, 2013, 78 (8), 3847–3857.
• 

74

• A new method for the protection of carboxylic acids with a triisopropylsiloxymethyl group.
• Yoshimura, Hikaru; Eto, Kohei; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi.
• Chemical & Pharmaceutical Bulletin, 2012, 60 (10), 1334-1339.
• 

73

• Organocatalytic asymmetric syntheses of inthomycins A, B and C.
• Yoshino, Madoka; Eto, Kohei; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi.
• Organic & Biomolecular Chemistry, 2012, 10 (40), 8164-8174.
• 

72

• Recent developments in the Reformatsky-Claisen rearrangement.
• Ishihara, Jun; Hatakeyama, Susumi.
• Molecules, 2012, 17, 14249-14259.
• 

71

• Stereocontrolled Total Synthesis of (-)-Englerin A.
• Takahashi, Keisuke; Komine, Keita; Yokoi, Yuichi; Ishihara, Jun; Hatakeyama, Susumi.
• Journal of Organic Chemistry, 2012, 77 (17), 7364-7370.
• 

70

• Stereoselective Synthesis of the Fused γ-lactone/δ-lactone Core of Ophiodilactones.
• Matsubara, Takaaki; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi.
• Heterocycles, 2012, 86 (1), 155-158.
• 

69

• Total Synthesis of (-)-Kaitocephalin Based on a Rh-Catalyzed C-H Amination.
• Takahashi, Keisuke; Yamaguchi, Daisuke; Ishihara, Jun; Hatakeyama, Susumi.
• Organic Letters, 2012, 14 (6), 1644-1647.
• 

68

• Indium-mediated Reformatsky-Claisen rearrangement.
• Ishihara, Jun; Watanabe, Yuki; Koyama, Noriko; Nishino, Yukihiro; Takahashi, Keisuke; Hatakeyama, Susumi.
• Tetrahedron, 2011, 67 (20), 3659-3667.
• 

67

• Organocatalytic asymmetric synthesis of quinine and quinidine.
• Sarkar, Shaheen M.; Taira, Yuko; Nakano, Ayako; Takahashi, Keisuske; Ishihara, Jun; Hatakeyama, Susumi.
• Tetrahedron Letters, 2011, 52 (8), 923-927.
• 

66

• Synthetic studies on vitamin D analogs. Part 39. Synthesis of 1-deoxyeldecalcitol, a biologically interesting analog of 1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (eldecalcitol).
• Sasaki, Hirotaka; Eto, Kohei; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi; Kubodera, Noboru.
• Heterocycles, 2011, 83 (6), 1385-1394.
• 

65

• Total synthesis of NW-G01, a cyclic hexapeptide antibiotic, and 34-epi-NW-G01.
• Shibahara, Setsuya; Matsubara, Takaaki; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi.
• Organic Letters, 2011, 13 (17), 4700-4703.
• 

64

• Total synthesis of oxazolomycin A.
• Eto, Kohei; Yoshino, Madoka; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi.
• Organic Letters, 2011, 13 (19), 5398-5401.
• 

63

• Synthesis and preliminary biological evaluation of 20-epi-eldecalcitol [20-epi-1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3: 20-epi-ED-71].
• Hatakeyama, Susumi; Yoshino, Madoka; Eto, Kohei; Takahashi, Keisuke; Ishihara, Jun; Ono, Yoshiyuki; Saito, Hitoshi; Kubodera, Noboru.
• Journal of Steroid Biochemistry and Molecular Biology, 2010, 121 (1-2), 25-28.

62

• Synthetic studies on vitamin D analogs. 37. Synthesis of 20-epi-1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3: 20-epi-ed-71].
• Yoshino, Madoka; Eto, Kohei; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi; Ono, Yoshiyuki; Saito, Hitoshi; Kubodera, Noboru.
• Heterocycles, 2010, 81 (2), 381-394.
• 

61

• Synthetic study on clutiolide based on a remote chelation controlled Ireland-Claisen rearrangement.
• Ishihara, Jun; Tokuda, Okihisa; Shiraishi, Kazunori; Nishino, Yukihiro; Takahashi, Keisuke; Hatakeyama, Susumi.
• Heterocycles, 2010, 80 (2), 1067-1079.
• 

60

• A new variant of Reformatsky-Claisen rearrangement mediated by indium chloride.
• Ishihara, Jun; Koyama, Noriko; Nishino, Yukihiro; Takahashi, Keisuke; Hatakeyama, Susumi
• Synlett, 2009, (14), 2351-2355.
• 

59

• Enantio- and stereoselective route to the phoslactomycin family of antibiotics: formal synthesis of (+)-fostriecin and (+)-phoslactomycin B.
• Sarkar, Shaheen M.; Wanzala, Everlyne N.; Shibahara, Setsuya; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi.
• Chemical Communications, 2009 (39), 5907-5909.
• 

58

• Enantioselective route to aryl(1,3-butadien-2-yl)methanols: formal synthesis of (-)-sporochnol A.
• Yanagimoto, Daisuke; Kawano, Kazuyuki; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi.
• Heterocycles, 2009, 77 (1), 249-253.
• 

57

• Synthetic studies of vitamin D analogs. Part 35. An improved synthesis of 1-epi-ED-71, a biologically interesting diastereomer of 1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (ED-71).
• Eto, Kohei; Fujiyama, Ayako; Kaneko, Mai; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi; Ono, Yoshiyuki; Kubodera, Noboru.
• Heterocycles, 2009, 77 (1), 323-331.
• 

56

• Total synthesis of (+)-fostriecin and (+)-phoslactomycin B.
• Shibahara, Setsuya; Fujino, Masataka; Tashiro, Yasumasa; Okamoto, Nanako; Esumi, Tomoyuki; Takahashi, Keisuske; Ishihara, Jun; Hatakeyama, Susumi.
• Synthesis, 2009, (17), 2935-2953.
• 

55

• Asymmetric synthesis of (+)-trachyspic acid.
• Morokuma, Kenji; Taira, Yuko; Uehara, Yumiko; Shibahara, Setsuya; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi.
• Tetrahedron Letters, 2008, 49 (42), 6043-6045.
• 

54

• Asymmetric Total Synthesis of (+)-Phoslactomycin B.
• Shibahara, Setsuya; Fujino, Masataka; Tashiro, Yasumasa; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi.
• Organic Letters,2008, 10 (11), 2139-2142.
• 

53

• Entry to heterocycles based on indium-catalyzed Conia-ene reactions: asymmetric synthesis of (-)-salinosporamide A.
• Takahashi, Keisuske; Midori, Michiko; Kawano, Kei; Ishihara, Jun; Hatakeyama, Susumi
• Angewandte Chemie, International Edition, 2008, 47 (33), 6244-6246.
• 

52

• Synthetic studies directed toward kaitocephalin: a highly stereocontrolled route to the right-hand pyrrolidine core.
• Takahashi, Keisuke; Haraguchi, Natsumi; Ishihara, Jun; Hatakeyama, Susumi.
• Synlett, 2008, (5), 671-674.
• 

51

• A highly stereocontrolled total synthesis of dysiherbaine.
• Takahashi, Keisuke; Matsumura, Takashi; Ishihara, Jun; Hatakeyama, Susumi.
• Chemical Communications, 2007 (40), 4158-4160.

50

• Synthesis and biological evaluation of a 3-position epimer of 1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (ED-71).
• Hatakeyama, Susumi; Nagashima, Satoshi; Imai, Naoko; Takahashi, Keisuke; Ishihara, Jun; Sugita, Atsuko; Nihei, Takeshi; Saito, Hitoshi; Takahashi, Fumiaki; Kubodera, Noboru.
• Journal of Steroid Biochemistry and Molecular Biology, 2007, 103 (3-5), 222-226.

49

• Synthesis of 1,3-diepi-ed-71, a biologically important diastereomer of 1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (ED-71).
• Fujiyama, Ayako; Kaneko, Mai; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi; Kubodera, Noboru.
• Heterocycles, 2007, 71 (10), 2263-2271.

48

• Total synthesis of Citrafungin A.
• Amer, Mumen F. A.; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi.
• Heterocycles, 2007, 72, 181-185.

47

• Total synthesis of neooxazolomycin.
• Onyango, Evans Otieno; Tsurumoto, Joji; Imai, Naoko; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi.
• Angewandte Chemie, International Edition, 2007, 46(35), 6703-6705.

46

• β-Isocupreidine-Catalyzed Baylis-Hillman Reaction of Chiral N-Boc-α-Amino Aldehydes
• Nakano, Ayako; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi.
• Organic Letters, 2006, 8(23), 5357-5360.

45

• A Highly Stereocontrolled Total Synthesis of (-)-Neodysiherbaine A
• Takahashi, Keisuke; Matsumura, Takashi; Corbin, Graeme R. M.; Ishihara, Jun; Hatakeyama, Susumi.
• Journal of Organic Chemistry, 2006, 71 (11), 4227-4231.

44

• Synthesis and evaluation of a 3-position diastereomer of 1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (ED-71).
• Hatakeyama, Susumi; Nagashima, Satoshi; Imai, Naoko; Takahashi, Keisuke; Ishihara, Jun; Sugita, Atsuko; Nihei, Takeshi; Saito, Hitoshi; Takahashi, Fumiaki; Kubodera, Noboru.
• Bioorganic & Medicinal Chemistry, 2006, 14 (23), 8050-8056.

43

• Synthesis of putative metabolites of 1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (ED-71)
• Ono, Yoshiyuki; Watanabe, Hiroyoshi; Taira, Ikuo; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi; Kubodera, Noboru.
• Steroids, 2006, 71 (7), 529-540.

42

• Total synthesis of (+)-β-erythroidine
• Fukumoto, Hironori; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi.
• Angewandte Chemie, International Edition, 2006, 45 (17), 2731-2734.

41

• Two convergent approaches to the synthesis of 1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (ED-71) by the lythgoe and the trost coupling reactions
• Maeyama, Junji; Hiyamizu, Hiroko; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi; Kubodera, Noboru.
• Heterocycles, 2006, 70, 295-307.

40

• Two convergent approaches to the synthesis of 1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (ED-71) by the lythgoe and the trost coupling reactions.
• Maeyama, Junji; Hiyamizu, Hiroko; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi; Kubodera, Noboru.
• Heterocycles, 2006, 70, 295-307.

39

• β-Isocupreidine-hexafluoroisopropyl acrylate method for asymmetric Baylis-Hillman reactions
• Nakano, Ayako; Kawahara, Sakie; Akamatsu, Saori; Morokuma, Kenji; Nakatani, Mari; Iwabuchi, Yoshiharu; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi.
• Tetrahedron, 2005, 62 (2-3), 381-389.

38

• Synthesis of a pseudoenantiomer of β-isocupreidine (β-ICD), a chiral amine catalyst for asymmetric Baylis-Hillman reactions
• Nakano, Ayako; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi.
• Heterocycles, 2005, 66, 371-383.

37

• Total synthesis of viridiofungin A.
• Morokuma, Kenji; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi.
• Chemical Communications, 2005 (17), 2265-2267.

36

• A concise route to (+)-lactacystin
• Ooi, Hidenori; Ishibashi, Norihisa; Iwabuchi, Yoshiharu; Ishihara, Jun; Hatakeyama, Susumi.
• Journal of Organic Chemistry, 2004, 69 (22), 7765-7768.

35

• Enantio- and stereocontrolled formation of the bisspiroacetal core of spirolide B
• Ishihara, Jun; Ishizaka, Tomoko; Suzuki, Takanori; Hatakeyama, Susumi.
• Tetrahedron Letters, 2004, 45 (42), 7855-7858.

34

• Synthesis of the Tricyclic Dihydrofuran Moiety of Azadirachtin: Efficient Transformation of the Claisen Rearrangement Intermediate into a Functionalized Tricyclic Dihydrofuran Core.
• Ishihara, J.; Ikuma, Y.; Hatakeyama, S.; Suzuki, T.; Murai, A.
• Tetrahedron, 2003, 59 (51), 10287-10294.

33

• Total Synthesis of (±)-Erythravine Based on Ring Closing Dienyne Metathesis.
• Fukumoto, H.; Esumi, T.; Ishihara, J.; Hatakeyama, S.
• Tetrahedron Lett., 2003, 44 (44), 8047-8049.

32

• Studies Aimed at the Total Synthesis of Azadirachtin. A Modeled Connection of C-8 and C-14 in Azadirachtin.
• Fukuzaki, T.; Kobayashi, S.: Hibi, T.; Ikuma, Y. ; Ishihara, J.; Kanoh, N.; Murai, A.
• Organic Letters, 2002, 4(17) 2877-2880.

31

• Asymmetric Construction of the Azaspiro[5.6]dodec-9-ene System in Marine Natural Toxins.
• Ishihara, J.; Horie, M.; Shimada, Y.; Tojo, S.; Murai A.
• Synlett, 2002, 3, 403-406.

30

• Asymmetric Construction of the Azaspiro[5.5]undec-8-ene System towards Gymnodimine Synthesis.
• Tsujimoto, T.; Ishihara, J.; Horie, M.; Murai, A.
• Synlett, 2002, 3, 399-402.

29

• On the Bioactive Conformation of the Rhodopsin Chromophore: Absolute Sense of Twist around the 6-s-cis Bond
• Fujimoto, Y.; Ishihara, J.; Maki, S.; Fujioka, N.; Tao, W.; Furuta, R.; Fishkin, N.; Borhan, B.; Berova, N.; Nakanishi, K.
• Chem. Eur. J.,2001, 7 (19), 4198-4204.

28

• One-step Assembling Reaction to the Pentacyclic Acetal of Pinnatoxins.
• Ishihara, J.; Tojo, S.; Kamikawa, A.; Murai, A.
• Chem. Commun., 2001, 15, 1392-1393.

27

• Facile Cleavage of Vicinal Tertiary Diols by Pyridinium Dichromate.
• Maki, S.; Ishihara, J. Nakanishi, K.
• J. Indian Chem. Soc., 2000, 77 (11-12), 651-655.

26

• Synthetic Studies on Azadirachtin: An Efficient Asymmetric Synthisis of the Highly Functionalized Tricyclic Decalin Part of Azdirachtin.
• Yamamoto, Y.; Ishihara, J.; Kanoh, N.; Murai, A.
• Synthesis, 2000, 13, 1894-1906.

25

• Synthetic Studies on Azadirachtin: Asymmetric Synthesis of the Tetracyclic Decalin Part of Azadirachtin.
• Kanoh, N.; Ishihara, J.; Yamamoto, Y.; Murai, A.
• Synthesis, 2000, 13, 1878-1893.

24

• Synthetic Studies of Viridenomycin. Construction of the Cyclopentene Carboxylic Acid Part.
• Ishihara, J.; Hagihara, K.; Chiba, H.; Ito, K.; Yanagisawa, Y.; Totani, K.; Tadano, K.
• Tetrahedron Lett., 2000, 41(11), 1771-1774.

23

• Synthesis of the B,C,D,E,F-Ring Fragment of Pinnatoxins.
• Sugimoto, T.; Ishihara, J. Murai.
• Synlett, 1999 (5), 541-544.

22

• Synthetic Studies on Azadirachtin: Construction of the Highly Functionalized Decalin Moiety of Azadirachtin.
• Ishihara, J.; Yamamoto, Y.; Kanoh, N.; Murai. A.
• Tetrahedron Lett., 1999, 40 (23), 4387-4390.

21

• Synthetic Studies on Azadirachtin (Part 3): Asymmetric Synthesis of the Tricyclic Dihydrofuran Moiety of Azadirachtin.
• Ishihara, J.; Fukuzaki T.; Murai, A.
• Tetrahedron Lett., 1999, 40 (10), 1907-1910.

20

• Studies on the Stability of 1,7,9-Trioxadispiro- [5.1.5.2]pentadecane System: The Common Tricyclic Acetal Moiety in Pinnatoxins.
• Ishihara, J. Sugimoto, T. Murai, A.
• Synlett, 1998 (6), 603-606.

19

• Total Synthesis of (-)-Verrucarol.
• Ishihara J.; Nonaka, R.; Terasawa, Y.; Shiraki, R.; Yabu, K.; Kataoka, H.; Ochiai, Y.; Tadano, K.
• J. Org. Chem., 1998, 63 (8), 2679-2688.

18

• Synthetic Study on Gymnodimine: Highly Stereoselective Construction of Substituted Tetrahydrofuran and Cyclohexene Moieties.
• Ishihara, J.; Miyakawa, J.; Tsujimoto, T.; Murai A.
• Synlett, 1997, 12, 1417-1419.

17

• Total Synthesis of (-)-Verrucarol, a Component of Naturally Occuring Verrucarin A.
• Ishihara, J.; Nonaka, R.; Terasawa, Y.; Shiraki, R.; Yabu, K.; Kataoka, H.; Ochiai, Y.; Tadano, K.
• Tetrahedron Lett., 1997, 38 (48), 8311-8314.

16

• Asymmetric Total Synthesis of Syringolide 1, a Nonproteinaceous Elicitor.
• Ishihara, J.; Sugimoto, T.; Murai, A.
• Tetrahedron, 1997, 53 (47), 16029-16040.

15

• The First Construction of the B,C,D-ring Fragment of Pinnatoxins via Highly Stereocontrolled Acetallization.
• Ishihara, J.; Sugimoto, T.; Murai, A.
• Tetrahedron Lett., 1997, 38 (42), 7379-7382.

14

• Conversion of Prelaureatin into Laurallene, a Bromo-Allene Compound, by Enzymatic and Chemical Bromo-Etherification Reactions.
• Ishihara, J.; Shimada, Y.; Kanoh, N.; Takasugi, .; Fukuzawa, A.; Murai A.
• Tetrahedron, 1997, 53 (25), 8371-8382.

13

• Synthetic Study on Azadirachtin: Asymmetric Synthesis of the Tetracyclic Decalin Part of Azadirachtin.
• Kanoh, N.; Ishihara, J.; Murai, A.
• Synlett, 1997, 6, 737-739.

12

• Absolute Construction of the Whole Mother Skeleton of Hemibrevetoxin-B.
• Ishihara, J.; Murai, A.
• Synlett, 1996, 4, 363-365.

11

• Asymmetric Synthesis of Syringolide 1, a Novel Nonproteinaceous Elicitor
• Ishihara, J.; Sugimoto, T.; Murai, A.
• Synlett, 1996, 4, 335-336.

10

• Construction of the Tricyclic trans-Decalin Framework of Azadirachitins via Intramolecular Diels-Alder Reaction.
• Kanoh, N.; Ishihara, J.; Murai, A.
• Synlett, 1995, 9, 895-897.

9

• Enzymatic Reaction of (3E,6S,7S)-Laurediol and the Modeling Studies on the Cyclization of Laurediols
• Ishihara, J.; Kanoh, N.; Murai, A.
• Tetrahedron Lett., 1995, 36 (5), 737-740.

8

• Synthesis Studies on the Trichothecene Family from D-Glucose.
• Ishihara, J.; Nonaka, R.; Terasawa, Y.; Tadano, K. Ogawa, S.
• Tetrahedron: Asymmetry,1994, 5(11), 2217-2232.

7

• Isomerization of the (Z)-Enyne Unit to the (E)-Enyne Unit. Conversion of Laureatin to (E)-Isolaureatin.
• Ishihara, J.; Kanoh, N.; Fukuzawa, A.; Murai, A.
• Chem. Lett., 1994, 1563-1564.

6

• Synthesis of Acetomycin- related (2R,3S,4R)- and (2S,3R,4R)-2-Acetoxy-4-acetyl-3,4-dimethyltetrahydrofuran and Their Growth Inhibition Activity against Tumor Cells.
• Ishihara, J.; Terato, N.; Sumino, A.; Tadano, K.; Ogawa, S.
• Bull. Chem. Soc. Jpn., 1993, 66 (5), 1441-1450.

5

• Total Syntheses of (-)-Acetomycin and Its Three Stereoisomers at C-4 and C-5.
• Ishihara, J.; Tomita, K.; Tadano, K.; Ogawa, S.
• J. Org. Chem., 1992, 57 (14), 3789-3798.

4

• A Route to 3,5-Dialkylated Carbohydrates: The Claisen Rearrangement of a 3-C-Methylated Aldose.
• Tadano K.; Shimada, K.; Ishihara, J.; Ogawa, S.
• J. Carbohydr. Chem., 1991, 10 (1), 1-10.

3

• Total Synthesis of (-)-Acetomycin.
• Tadano K.; Ishihara, J.; Ogawa, S.
• Tetrahedron Letters, 1990, 31 (18), 2609-2612.

2

• Claisen Rearrangements of 5,6-Dideoxy-1,2-O-isopropylidene-α-D-xylo- and α-D-ribo-Hept-5-eno-1,4-furanoses with Triethyl Orthoacetate.
• Tadano K.; Shimada, K.; Miyake, A.; Ishihara, J.; Yamada, H.; Ogawa, S.
• Bull. Chem. Soc. Jpn., 1989, 62 (12), 3978-3986.

1

• Claisen Rearrangement of (Z)-3- Deoxy-3-C-[(hydroxymethyl)methylene]-1,2:5,6-di-O-isopropylidene-α-D-ribo-hexofuranose with Triethyl Orthopropionate.
• Tadano K.; Ishihara, J.; Yamada, H.; Ogawa, S.
• J. Org. Chem., 1989, 54 (5), 1223-1227.

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