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Research

  • Development of targeted drug delivery system using physical stimuli
  • Design and evaluation of ligand modified liposomes
  • Development of gene delivery system and its application
  • Evaluation of pharmaceutical products for effective and safe use

Research Achievements

Latest update: Mar 20, 2018

Research Achievements (2019)

Publication

English, Original papers

  1. Yusuke Miura, Yuki Fuchigami, Sakiko Nomura, Koyo Nishimura, Masayori Hagimori, and Shigeru Kawakami†: Brain microdialysis study of vancomycin in the cerebrospinal fluid after intracerebroventricular administration in mice, AAPS PharmSciTech, 20, 5 (2019) (IF: 2.666) (†: corresponding author)
  2. Tadaharu Suga, Masanori Watanabe, Yuri Sugimoto, Tomonari Masuda, Naotaka Kuroda, Masayori Hagimori, and Shigeru Kawakami†: Synthesis of a high functionality and quality lipid with gp130 binding hydrophobic peptide for the preparation of human glioma cell-targeted PEGylated liposomes (†: corresponding author), Journal of Drug Delivery Science and Technology, 49, 668-673 (2019) (IF: 2.297)
  3. Kaname Ohyama, Yuka Ikeshita, Yuki Fuchigami, Shigeru Kawakami, Mihoko N. Nakashima, and Mikiro Nakashima: Proteomic analysis and ATP assay reveal a positive effect of artificial cerebral spinal fluid perfusion following microdialysis sampling on repair of probe-induced brain damage, Journal of Neuroscience Methods, 315, 1-5 (2019) (IF: 2.668)
  4. Koki Ogawa, Yuki Fuchigami, Masayori Hagimori, Shintaro Fumoto, Kazuo Maruyama, Shigeru Kawakami†: Ultrasound-responsive nanobubble-mediated gene transfection in the cerebroventricular region by intracerebroventricular administration in mice, European Journal of Pharmaceutics and Biopharmaceutics, 137, 1-8 (2019) (IF: 4.491)

Japanese

Conference presentation

Invited

  1. 川上 茂、菅 忠明:多色深部イメージングを利用した空間分布制御型ナノDDSの開発、日本薬学会139年会、千葉、2019年3月22日
  2. Others

    1. 萩森 政頼、狩峯 寧、小野 亜佳莉、加藤 直也、水山 奈央子、川上 茂: 亜鉛検出用蛍光ナノ粒子の合成および基礎的評価、第18回日本亜鉛栄養治療研究会、2019年2月2日、大阪
    2. 菅 忠明、内山詩乃、増田智成、萩森政頼、川上 茂:膵癌深部への送達を目的とする微小な膵癌指向型リポソーム製剤の開発、日本薬学会139年会、千葉、2019年3月21日
    3. 大山奈津子、川口真帆、鶴丸雅子、萩森政頼、川上 茂:腎臓への圧力刺激を利用した遺伝子導入法:輸尿管投与・腎動脈投与後の腎臓内遺伝子発現と空間分布特性の解明、日本薬学会139年会、千葉、2019年3月22日

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