論文発表
2021年
1.
Yamaberi Y,
Eto R, Umeno T, Kato T, Doi M, Yokoo H, Oba M, Tanaka M: Synthesis of
(S)-(-)-Cucurbitine and Conformation of Its Homopeptides. Org. Lett. 2021,
23, 4358-4362 (Supplementary cover) .
2.
Makura Y, Ueda A, Kato T, Iyoshi A,
Higuchi M, Doi M, Tanaka M: X-ray
crystallographic structure of α-helical peptide stabilized by hydrocarbon stapling
at i, i+1 positions. Int.
J. of Mol. Sci., 2021, 22, 5364.
3.
Sato K, Umeno T, Ueda A, Kato T,
Doi M, Tanaka M, Asymmetric 1,4-addition reactions catalyzed by
N-terminal thiourea-modified helical L-Leu-peptide with cyclic amino acids. Chem. Eur. J. 2021, 27, 11216-11220.
4.
Kato T, Kita Y, Iwanari K, Asano A, Oba M, Tanaka M, Doi M: Synthesis
of six-membered carbocyclic ring α,α-disubstituted amino acids and
arginine-rich peptides to investigate the effect of ring size on the properties
of the peptide. Bioorg. Med. Chem., 2021, 38,
116111/
5.
Uchida S, Yamaberi Y, Tanaka M, Oba M: A helix foldamer
oligopeptide improves intracellular stability and prolongs protein expression
of delivered mRNA. Nanoscale, 2021, in press.
2020年
Furukawa K, Tanaka M, Oba M: siRNA
delivery using amphipathic cell-penetrating peptides into human hepatoma cells. Bioorg Med Chem 28: 115402, 2020.
5.
Ueda
A, Pi J, Makura Y, Tanaka M, Uenishi, J: Stereoselective synthesis of (+)-5-thiosucrose
and (+)-5-thioisosucrose.
RSC Advances 10: 9730-9735, 2020.
6.
Tsuchiya K, Umeno T, Tsuji G, Yokoo H, Tanaka M, Fukuhara K, Demizu Y, Misawa T: Development
of photoswitchable estrogen receptor ligands. Chem
Pharm Bull,
68(4), 398-402, 2020.
7.
Ueda
A, Ikeda M, Kasae T, Doi M, Demizu Y, Oba M, Tanaka M: Synthesis of chiral α-trifluoromethyl α,α-disubstituted α-amino
acids and conformational analysis of L-Leu-based peptides with (R)- or
(S)-α-trifluoromethylalanine. ChemSelect 5: 10882-10886, 2020.
8.
Ueda
A, Higuchi M, Sato K, Umeno T, Tanaka M: Design and
synthesis of helical N-terminal L-prolyl oligopeptides possessing hydrocarbon
stapling. Molecule 25: 4667, 2020.
2019年
9. Oba M, Nagano Y, Kato T, Tanaka M: Secondary structures
and cell-penetrating abilities of arginine-rich peptide foldamers. Sci Rep 9:
1349, 2019.
10. Oba M, Ito Y, Umeno T, Kato T, Tanaka M: Plasmid DNA
delivery using cell-penetrating peptide foldamers composed of Arg-Arg-Aib
repeating sequences. ACS Biomater Sci Eng 5: 5660-5668, 2019.
11. Misawa T, Ohoka N, Oba M, Yamashita H, Tanaka M, Naito M,
Demizu Y: Development of 2-aminoisobutyric acid (Aib)-rich cell-penetrating
foldamers (CPFs) for efficient siRNA delivery. Chem Commun 55: 7792-7795, 2019.
12. Umeno T, Ueda A, Doi M, Kato T, Oba M, Tanaka M: Helical
foldamer-catalyzed enantioselective 1,4-addition reaction of dialkyl malonates
to cyclic enones. Tetrahedron Lett 60: 151301, 2019.
13. Ueda A, Higuchi M, Umeno T, Tanaka M: Enantioselective
synthesis of 2,4,5-trisubstituted tetrahydropyrans via peptide-catalyzed
Michael addition followed by Kishi’s reductive cyclization. Heterocycles 99:
989-1002, 2019.
14. Makura Y, Ueda A, Matsuzaki T, Minamino T, Tanaka M:
α-Selective glycosidation of D-tagatofuranose with a 3,4-O-isopropylidene protection. Tetrahedron 75: 3758-3766, 2019.
2018年
15. Oba M, Ito C, Tanaka M: Effects of five-membered ring
amino acid incorporation into peptides for coiled coil formation. Bioorg Med
Chem Lett 28 (5): 875-877, 2018.
16. Kobayashi H, Misawa T, Oba M, Hirata N, Kanda Y, Tanaka
M, Matsuno K, Demizu Y: Structural development of cell-penetrating peptides
containing cationic proline derivatives. Chem Pharm Bull 66 (5): 575-580, 2018.
17. Kato T, Oba M, Nishida K, Tanaka M: Cell-penetrating
peptides using cyclic a,a-disubstituted a-amino acids with basic functional groups. ACS Biomat Sci
Eng 4 (4): 1368-1376, 2018.
18. Tanaka M, Yakabi H, Nakatani H, Ueda A, Doi M, Oba M:
Helical structures of cyclopentene-based a,a-disubstituted a-amino acid homopeptides.
Chimia 72 (12): 848-852, 2018.
19. Koba Y, Ueda A, Oba M, Doi M, Kato T, Demizu Y, Tanaka M:
Left-handed helix of three-membered ring amino acid homopeptide interrupted by
an N–H···ethereal O type hydrogen bond. Org Lett 20 (24): 7830-7834, 2018.
20. Ueda A, Nishimura Y, Makura Y, Tanaka M, Uenishi J: b-Selective
D-psicofuranosylation of pyrimidine bases and thiols. Heterocycles 97 (2):
729-743, 2018.
21. Wang S, Fumoto S, Miyamoto H, Tanaka M, and Nishida K:
Edaravone, a cytoprotective drug, enhances transgene expression mediated by
lipoplexes in HepG2 cells and mice. Int J Pharm 548 (1): 173-181, 2018.
2017年
22.
Yamashita H, Misawa T, Oba M, Tanaka M, Naito M,
Kurihara M, Demizu Y: Development of helix-stabilized cell-penetrating peptides
containing cationic a,a-disubstituted amino
acids as helical promoters. Bioorg Med Chem 25(6): 1846-1851, 2017.
23.
Oba M, Kunitake M, Kato T, Ueda A, Tanaka M:
Enhanced and prolonged cell-penetrating abilities of arginine-rich peptides by
introducing cyclic a,a-disubstituted a-amino acids with stapling. Bioconjugate Chem 28(7): 1801-1806,
2017.
24.
Furukawa K, Oba M, Toyama K, Opiyo GO, Demizu Y,
Kurihara M, Doi M, Tanaka M: Low pH-triggering changes in peptide secondary
structures. Org Biomol Chem 15(30): 6302-6305, 2017 (Cover picture).
25.
Koba Y, Ueda A, Oba M, Doi M, Demizu Y, Kurihara
M, Tanaka M: Helical L-Leu-based peptides having chiral five-membered
carbocyclic ring amino acids with an ethylene acetal moiety. ChemistrySelect 2:
8108-8114, 2017.
26. Eto R,
Oba M, Ueda A, Uku T, Doi M, Matsuo Y, Tanaka T, Demizu Y, Kurihara M, Tanaka
M: Diastereomeric right- and left-handed helical structures with fourteen (R)-chiral centers. Chem Eur J 23(72): 18120-18124, 2017.
27. Chen Q, Osada K, Ge Z,
Uchida S, Tockary TA, Dirisala A, Matsui A, Toh K, Takeda KM, Liu X, Nomoto T,
Ishii T, Oba M, Matsumoto Y, Kataoka K: Polyplex
micelle installing intracellular self-processing functionalities without free
catiomers for safe and efficient systemic gene therapy through tumor
vasculature targeting. Biomaterials 113: 253-265, 2017.