研究業績


2023 2022 2021 2020 2019 2018 2017  2016  2015  2014  2013  2012  2011  2010  2009  2008  2007  2006  2005〜


2023

論文


1.  Kaladari F, El-Maghrabey MH, Kishikawa N, Kuroda N:
Development of signal multiplication system for quinone linked immunosorbent assay (Multi-QuLISA) by using poly-L-lysine dendrigraft and 1,2-naphthoquinone-4-sulfonate as enzyme-free tag.
Talanta 253: 123911, 2023. (IF: 6.556)

2. Kishikawa N, El-Maghrabey MH, Tobo M, Kuroda N:
A Comparative Study on the Reduction Modes for Quinone to Determine Ubiquinone by HPLC with Luminol Chemiluminescence Detection Based on the Redox Reaction.
Molecules 28(1): 96, 2023. (IF: 4.927)

3. Kishikawa N, El-Maghrabey MH, Kawamoto A, Ohayama K, Kuroda N:
Determination of Anthraquinone-Tagged Amines Using High-Performance Liquid Chromatography with Online UV Irradiation and Luminol Chemiluminescence Detection.
Molecules 28(5): 2146, 2023. (IF: 4.927)

4. Kaladari F, Kishikawa N, Shimada A, El-Maghrabey MH, Kuroda N:
Anthracycline-Functionalized Dextran as a New Signal Multiplication Tagging Approach for Immunoassay.
Biosensors 13(3): 340, 2023. (IF: 5.743)

5.  Tange A, Kishikawa N, Sakamoto Y, El-Maghrabey MH, Wada M, Kuroda N:
A Turn-On Quinazolinone-Based Fluorescence Probe for Selective Detection of Carbon Monoxide .
Molecules 28(9): 3654, 2023. (IF: 4.927)

6 Takada M, Saruwatari S, Yanagita Y, Mutoh J, Harada H, Kishikawa N, Kitahara T, Kuroda N, Wada M:
Analysis of vaporized caffeine in smoke from e-cigarettes using liquid chromatography-tandem mass spectrometry and clarification of minor components.
Forensic Toxicology 41(1): 135-141, 2023 (IF: 2.541)




2022

論文

1.  Kishikawa N:
Liquid Chromatographic Techniques in Food Sciences.
Chemical and Pharmaceutical Bulletin 70(1): 10-11, 2022. (IF: 1.903)

2. Fukuda M, Kishikawa N, Samemoto S, Ohta K, Ohyama K, El-Maghrabey MH, Ikemoto K, Kuroda N:
Determination Method for Pyrroloquinoline Quinone in Food Products by HPLC-UV Detection Using a Redox-Based Colorimetric Reaction.
Chemical and Pharmaceutical Bulletin 70(1): 32-36, 2022. (IF: 1.903)

3. Takada M, Sakamoto  M, Yamada H, Kishikawa N, Mutoh J, Shiraishi Y, Kuroda N, Wada M:
HPLC Fluorescence Method for Eugenols in Basil Products Derivatized with DIBI.
Chemical and Pharmaceutical Bulletin 70(1): 37-42, 2022. (IF: 1.903)

4.  Okamoto Y, Kishikawa N, Hagimori M, El-Maghrabey MH, Kawakami S, Kuroda N:
A turn-on hydrazide oxidative decomposition-based fluorescence probe for highly selective detection of Cu2+ in tap water as well as cell imaging.
Analytica Chimica Acta 1217: 340024, 2022. (IF: 6.911)

5. El-Maghrabey MH, Sato Y, Kaladari F, Kishikawa N, Kuroda N:
Development of quinone linked immunosorbent assay (QuLISA) based on using Folin's reagent as a non-enzymatic tag: Application to analysis of food allergens.
Sensors and Actuators B: Chemical 368: 132167, 2022. (IF: 9.211)

6. 岸川直哉、沼田 翔、梅野智大、EL-MAGHRABEY Mahmoud、大 山 要、田中正一、黒田直敬:
非天然型アミノ酸を含むペプチドに より修飾した HPLC 固定相の調製とその評価.
分析化学 71(6): 351-356, 2022. (IF: 0.231)

7. Kishikawa N, El-Maghrabey MH, Tsubokami A, Hori H, Kuroda N:
Development of a selective assay of tyrosine and its producing and metabolizing enzymes utilizing pulse-UV irradiation-induced chemiluminescence.
Analytical Chemistry 94: 11529-11537, 2022. (IF: 8.008)

8. Nakano-Yasaka N, Kishikawa N, El-Maghrabey MH, Kuroda N:
Development of a selective fluorescence derivatization strategy for thyroid hormones based on the Sonogashira coupling reaction.
Journal of Chromatography A 1681: 463275, 2022. (IF: 4.601)

9. Fukuda T, Iwata H, Kishikawa N, El-Maghrabey MH, Ohyama K, Kawakami S, Wada M, Kuroda N:
Selective fluorescence labeling of myristicin using Mizoroki-Heck coupling reaction. Application to nutmeg powder, oil, and human plasma samples.
Journal of Chromatography A 1681: 463465, 2022. (IF: 4.601)





2021

論文

1. El-Maghrabey MH, Kishikawa N, Kamimura S, Ohyama K, Kuroda N:
Design of a dual functionalized chemiluminescence ultrasensitive probe for quinones based on their redox cycle. Application to the determination of doxorubicin in lyophilized powder and human serum.
Sensors and Actuators B: Chemical 329: 129226, 2021. (IF: 7.460)

2. Tange A, Higashi A, Kishikawa N, Kuroda N:
Simple fluorescence assay for triethylamine based on the palladium catalytic dimerization of benzofuran-2-boronic acid.
Analytical Sciences 37: 1465-1467, 2021. (IF: 2.081)

3. El-Maghrabey MH, Suzuki H, Kishikawa N, Kuroda N:
A sensitive chemiluminescence detection approach for determination of 2,4-dinitrophenylhydrazine derivatized aldehydes using online UV irradiation ? luminol CL reaction. Application to the HPLC analysis of aldehydes in oil samples.
Talanta, 233: 122522, 2021. (IF: 6.057)

4. Aibara N, Ohyama K, Nakamura M, Nakamura H, Tamai M, Kishikawa N, Kawakami A, Tsukamoto K, Nakashima M, Kuroda N:
Investigation of immune complexes formed by mitochondrial antigens containing a new lipoylated site in sera of primary biliary cholangitis patients.
Clinical and Experimental Immunology, 204: 335-343, 2021. (IF: 4.330)

著書

1. El-Maghrabey MH, El Hamd MA, El-Shaheny R,  Kishikawa N, Kuroda N:
Green solvents for  radionuclides extraction.
Green Sustainable Process for Chemical and Environmental Engineering and Science, 121-147, 2021.

そのほか

1. 岸川直哉: 標的への酵素標識ではなく酵素活性付与に 基づくバイオセンシングシステム.ぶんせき 2021(11): 682-683, 2021.

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2020

論文

1. Ali MFB, Kishikawa N, Kuroda N:
Development of HPLC method for estimation of glyoxylic acid after pre-column fluorescence derivatization approach based on thiazine derivative formation: A new application in healthy and cardiovascular patients’ sera.
Journal of Chromatography B 1143: 122054, 2020. (IF: 3.004)

2. Higashijima T, Kishikawa N, Kuroda N:
Long-wavelength fluorogenic derivatization of aryl halides based on the formation of stilbene by Heck reaction with vinylbenzenes.
Analytical Sciences, 36: 997-1001, 2020. (IF: 2.049)

3. El-Maghrabey MH, Kishikawa N, Harada S, Ohyama K, Kuroda N:
Quinone-based antibody labeling reagent for enzyme-free chemiluminescent immunoassays. Application to avidin and biotinylated anti-rabbit IgG labeling.
Biosensors and Bioelectronics 160: 112215, 2020. (IF: 10.257)

4. Kishikawa N, El-Maghrabey MH, Nagamune Y, Nagai K, Ohyama K, Kuroda N:
A smart advanced chemiluminescence-sensing platform for determination and imaging of the tissue distribution of natural antioxidants.
Analytical Chemistry, 6984-6992, 2020. (IF: 6.785)

5. Ali MFB, Uejo Y, Kishikawa N, Ohyama K, Kuroda N:
A selective and highly sensitive high performance liquid chromatography with fluorescence derivatization approach based on Sonogashira coupling reaction for determination of ethinyl estradiol in river water samples.
Journal of Chromatography A, 461440, 2020. (IF: 4.049)

総説
1. El-Maghrabey MH, Kishikawa N, Kuroda N:
Current trends in isotope-coded derivatization liquid chromatographic-mass spectrometric analyses with special emphasis on their biomedical application.
Biomedical Chromatography 34(3), e4756, 2020. (IF: 1.728)

2. El-Maghrabey MH, Kishikawa N, Kuroda N:
Utility of isotope-coded derivatization in gas chromatographic-mass spectrometric analyses with special emphasis on metabolomics.
Medical Mass Spectrometry 4(1), 2020.

著書

1. El-Maghrabey MH, El-Shaheny R,  Belal R, Kishikawa N, Kuroda N:
Green Sensors for Environmental Contaminants.
Nanotechnology in the Life Sciences, 491-516, 2020.

2019

論文
1. Fukuda M, Qianjun L, Kishikawa N, Ohyama K, Kuroda N:
    Development of ultrafast colorimetric microplate assay method for ubiquinone utilizing the redox cycle of the quinone.
    Microchemical Journal 150: 104104, 2019. (IF: 3.206)

2. El-Maghrabey MH, Watanabe R, Kishikawa N, Kuroda N:
    Detection of hydrogen sulfide in water samples with 2-(4-hydroxyphenyl)-4,5-di(2-pyridyl)imidazole-copper(II) complex using environmentally green microplate fluorescence assay method.
    Analytica Chimica Acta 1057: 123-131, 2019. (IF: 5.256)

3. Peng JQ, Fumoto S, Suga T, Miyamoto H, Kuroda N, Kawakami S, Nishida, K:
    Targeted co-delivery of protein and drug to a tumor in vivo by sophisticated RGD-modified lipid-calcium carbonate nanoparticles.
    Journal of Controlled Release 302: 45-53, 2019. (IF: 7.901)

4. Suga T, Watanabe M, Sugimoto Y, Masuda T, Kuroda N, Hagimori M, Kawakami S:
    Synthesis of a high functionality and quality lipid with gp130 binding hydrophobic peptide for the preparation of human glioma cell-targeted PEGylated liposomes.
    Journal of Drug Delivery Science and Technology 49: 668-673, 2019. (IF: 2.606)

総説
1. Kishikawa N, El-Maghrabey MH, Kuroda N:
    Chromatographic methods and sample pretreatment techniques for aldehydes determination in biological, food, and environmental samples.
    Journal of Pharmaceutical and Biomedical Analysis 175: 112782, 2019. (IF: 2.983)


そのほか

1. 岸川直哉: 安全安心な一酸化炭素の検出を目的とするメタルフリー型蛍光プローブ.ファルマシア 55(12): 1167, 2019.

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2018

論 文

1. Kishikawa N, Yamanouchi A, El-Maghrabey MH, Ohyama K, Kuroda N:

 Determination of tanshinones in Danshen (Salvia miltiorrhiza) by high-performance liquid chromatography with fluorescence detection after pre-column derivatisation.

 Phytochemical Analysis 29: 112-117, 2018. (IF: 2.337)


2. Yasaka N, Kishikawa N, Higashijima T, Ohyama K, Kuroda N:

 The utility of Sonogashira coupling reaction for the derivatization of aryl halides with fluorescent alkyne.

 Analytical Sciences 34: 1183-1188, 2018. (IF: 1.355)


3. El-Maghrabey MH, Mine M, Kishikawa N, Ohyama K, Kuroda N:

 A novel dual labeling approach enables converting fluorescence labeling reagents into fluorogenic ones via introduction of purification tags. Application to determination of glyoxylic acid in serum.

 Talanta 180: 323-328, 2018. (IF: 4.244)


4. Ichinose K, Ohyama K, Furukawa K, Higuchi O, Mukaino A, Satoh K, Nakane S, Shimizu T, Umeda M, Fukui S, Nishino A, Nakajima H, Koga T, Kawashiri SY, Iwamoto N, Tamai M, Nakamura H, Origuchi T, Yoshida M, Kuroda N, Kawakami A:

 Novel anti-suprabasin antibodies may contribute to the pathogenesis of neuropsychiatric systemic lupus erythematosus.

 Clinical Immunology 193: 123-130, 2018. (IF: 3.557)


5. Aibara, N, Ohyama K, Hidaka M, Kishikawa N, Miyata Y, Takatsuki M, Eguchi S, Kuroda N:

 Immune complexome analysis of antigens in circulating immune complexes from patients with acute cellular rejection after living donor liver transplantationdetection.

 Transplant Immunology 48: 60-64, 2018. (IF: 1.655)


6. Aibara, N, Ichinose K, Baba M, Nakajima H, Satoh K, Atarashi R, Kishikawa N, Nishida N, Kawakami A, Kuroda N, Ohyama K:

 Proteomic approach to profiling immune complex antigens in cerebrospinal fluid samples from patients with central nervous system autoimmune diseases.

 Clinica Chiimca Acta 484: 26-31, 2018. (IF: 2.926)


7. El-Maghrabey MH, Nakatani T, Kishikawa N, Kuroda N:

 Aromatic aldehydes as selective fluorogenic derivatizing agents for α-dicarbonyl compounds. Application to HPLC analysis of some advanced glycation end products and oxidative stress biomarkers in human serum.

 Journal of Pharmaceutical and Biomedical Analysis 158: 38-46, 2018. (IF: 2.831)


8. Aibara, N, Kamohara C, Chauhan AK, Kishikawa N, Miyata Y, Nakashima M, Kuroda N, Ohyama K:

 Selective, sensitive and comprehensive detection of immune complex antigens by immune complexome analysis with papain-digestion and elution.

 Journal of Immunological Methods 461: 85-90, 2018. (IF: 2.190).


9. Suga T, Kato N, Hagimori M, Fuchigami Y, Kuroda N, Kodama Y, Sasaki H, Kawakami S:

 Development of high functionality and quality lipids with RGD peptide ligands: application for PEGylated liposomes and analysis of intratumoral distribution in a murine colon cancer model.

 Molecular Pharmaceutics 15: 4481-4490, 2018. (IF: 4.556)


10. El-Maghrabey MH, Kishikawa N, Kuroda N:

 Novel isotope-coded derivatization method for aldehydes using 14N/15N-ammonium acetate and 9,10-phenanthrenequinone. 

 Analytical Chemistry 90: 13867-13875, 2018. (IF: 6.042)

 

  総説

1. Kishikawa N:

 Derivatization techniques for chromatographic analysis.

 Analytical Sciences 34: 1109-1110, 2018. (IF: 1.355)



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2017


[1]Redox-based chemiluminescence assay of aminothiols in human urine: A fundamental study.

    Elgawish MS, Kishikawa N, Kuroda N

    Talanta 164: 116-120, 2017.


[2] Immune complexome analysis reveals the specific and frequent presenceof immune complex antigens in lung     cancer patients: A pilot study.

    OhyamaK, Yoshimi H, Aibara N, Nakamura Y, Miyata Y, Sakai H, Fujita F, Imaizumi Y, Chauhan AK,  Kishikawa N, Kuroda N

    International Journal of Cancer 140(2): 370-380, 2017.


[3] Luminol chemiluminescence profile of O/W emulsions during thermal oxidation.

    Wada M, Yamaguchi A, Ogawa A, Kido H,  Nakamura S,Takada M, Kawakami S, Kuroda N, Nakashima, K

    Analytical Sciences 33(2): 249-252, 2017.


[4]A simple and highly selective fluorescent sensor for palladium based on benzofuran-2-boronic acid.

    Higashi A, Kishikawa N, Ohyama K, Kuroda N

    Tetrahedron Letters 58: 2774-2778, 2017.


[5]Ultrasensitive determination of pyrroloquinoline quinone in human plasma by HPLC withchemiluminescence detection using the redox cycle of quinone.

    Fukuda M, El-Maghrabey MH, Kishikawa N, Ikemoto K, Kuroda N

    Journal of Pharmaceutical and Biomedical Analysis 145: 814-820, 2017.


[6]Development of an evaluation method for hydroxyl radical scavenging activitiesusing sequential injection analysis with chemiluminescence detection.

   Miyamoto A, Nakano S, Nagai K, Kishikawa N, Ohyama K, Aoyama T, Matsumoto Y, Kuroda N

    Analytical Sciences 33: 697-701, 2017.


[7] One-step formation of lipid-polyacrylic acid-calcium carbonate nanoparticles for co-delivery of doxorubicin and curcumin.

    Peng J, Fumoto S, Miyamoto H, Chen Y, Kuroda N, Nishida K

    Journal of Drug Targeting 25: 704-714, 2017.


[8] 脂質過酸化アルデヒドをマーカーとする酸化ストレス疾患の新規評価法の開発
   
岸川直哉、黒田直敬

    臨床化学 46:299-304, 2017.



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2016[PDF]

[1] Immune complexome analysis of antigens in circulating immune complexes isolated from patients with IgG4-related dacryoadenitis and/or sialadenitis.

    Ohyama K, Baba M, Tamai M,  Yamamoto M,  Ichinose K,  Kishikawa N,  Takahashi H,  Kawakami A, Kuroda N

    Modern Reumatology 26(2):248-250, 2016.


[2] Quantitative and antioxidative behavior of Trolox in rats' blood and brain by HPLC-UV and SMFIA-CL methods.

      Wada M, Ikeda R, Fuchigami Y, Koyama H,  Ohkawara S,  Kawakami S, Kuroda N, Nakashima K

      Luminescence 31(2):414-418, 2016.


[3] Spatial correlativity of atmospheric particulate components simultaneously collected in Japan.

      Funasaka K, Asakawa D, Oku Y, Kishikawa N, Deguchi Y, Sera N, Seiyama T, Horasaki K, Arashidani K, Toriba A, Hayakawa K, Watanabe M, Kataoka H, Yamaguchi T, Ikemori F, Inaba Y, Tonokura K, Akiyama M, Kokunai O, Coulibaly S, Hasei T, Watanabe T

     Environmental Monitoring and Assessment 188(2):1-14, 2016.


[4] Proteomic profile of circulating immune complexes in chronic Chagas disease.

      Ohyama K, Huy NT, Yoshimi H, Kishikawa N, Nishizawa JE, Roca Y, Revollo Guzm?n RJ, Velarde FU, Kuroda N, Hirayama K

      Parasite Immunology 38(10): 609-617, 2016.


[5] 9,10-Phenanthrenequinone as a mass-tagging reagent for ultra-sensitive liquid chromatography?tandem mass spectrometry assay of aliphatic aldehydes in human serum.

      El-Maghrabey MH, Kishikawa N, Kuroda N

      Journal of Chromatography A 1462: 80-89, 2016.


[6] 機能性食品及びサプリメントの有効成分の分析と機能性評価
    和田光弘、黒田直敬、中島憲一郎

    分析化学 65(6):301-308, 2016.


[7] 毒物を検出するための蛍光プローブ
    岸川直哉

    ぶんせき 7:267-274, 2016.




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2015 [PDF]

[1] Proteomic profiling of antigens in circulating immune complexes associated with each of seven autoimmune diseases.

    Ohyama K, Baba M, Tamai M, Aibara N, Ichinose K, Kishikawa N, Kawakami A, Kuroda N

    Clinical Biochemistry 48(3):181-185, 2015.


[2] Simultaneous determination of propofol and remifentanil in rat plasma by liquid chromatography-tandem mass spectrometry: Application to preclinical pharmacokinetic drug-drug interaction analysis.

    El Hamd MA, Wada M, Ikeda R, Kawakami S, Kuroda N, Nakashima K

    Biomedical Chromatography 29(3):325-327, 2015.


[3] Poly(L-lactic acid)-modified silica stationary phase for reversed-phase and hydrophilic interaction liquid chromatography.

    Ohyama K, Takasago S, Kishikawa N, Kuroda N

    Journal of Separation Science 38(5):720-723, 2015.


[4] Determination of acrolein in serum by high-performance liquid chromatography with fluorescence detection after pre-column fluorogenic derivatization using 1,2-diamino-4,5-dimethoxybenzene.

    Imazato T, Kanematsu M, Kishikawa N, Ohyama K, Hino T, Ueki Y, Maehata E, Kuroda N

    Biomedical Chromatography 29: 1304-1308, 2015.


[5] Evaluation of the neurochemical effects of methoxetamine using brain microdialysis in mice.

    Fuchigami Y, Fu X,  Ikeda R, Kawakami S, Wada M, Kikura-Hanajiri R,  Kuroda N, Nakashima, K

    Forensic Toxicology 33(2): 374-379, 2015.


[6] Determination of human serum semicarbazide-sensitive amine oxidase activity via flow injection analysis with fluorescence detection after online derivatization of the enzymatically produced benzaldehyde with 1,2-diaminoanthraquinone.

    El-Maghrabey MH, Kishikawa N, Ohyama K, Imazato T,  Ueki Y,  Kuroda, N

    Analytica Chimica Acta 881: 139-147, 2015.


[7] 化学発光法に基づく生体内活性酸素産生物質の解析
    岸川直哉、黒田直敬

    薬学雑誌, 135(2):191-126, 2015.


[8] 生命現象の解明に 有用な分析ツールの創製
    岸川直哉、轟木堅一郎

    薬学雑誌, 135(2):189-190, 2015.


[9] Molecular modeling and spectroscopic study of quinone-protein adducts: insight into toxicity, selectivity, and reversibility.

      Elgawish MS, Kishikawa N, Ohyama K, Kuroda N

      Toxicology Research 4: 843-847, 2015.


[10] Characterization of quinone derived protein adducts and their selective identification using redox cycling based chemiluminescence assay.

        Elgawish MS, Kishikawa N, Heral MA, Ohyama K, Kuroda N

        Journal of Chromatography A 1403: 96-103, 2015.


[11]  Quinones as novel chemiluminescent probes for the sensitive and selective determination of biothiols in biological fluids.

         Elgawish MS, Kishikawa N, Kuroda N

         Analyst 140: 8148-8156, 2015.


[12] Molecular-shape selectivity by naphthalimido-modified silica stationary phases: Insight into the substituents effect of naphthalene on shape recognition and π- π interactions via electrostatic potential.

       Yamada Y, Ohyama K, Onodera G, Kuriyama M, Kishikawa N, Kuroda N

       Journal of Chromatography A 1425: 173-179, 2015.


[13] Upregulation of thrombospondin 1 expression in synovial tissues and plasma of rheumatoid arthritis: role of transforming growth factor-β1 toward fibroblast-like synovial cells.

        Suzuki T, Iwamoto N, Yamasaki S, Nishino A, Nakashima Y, Horai Y, Kawashiri S, Ichinose K, Arima K, Tamai M, Nakamura H, Origuchi T, Miyamoto C, Osaki M, Ohyama K, Kuroda N, Kawakami A

       Journal of Rheumatology 42: 943-947, 2015.


[14] Simultaneous determination of propofol and remifentanil in rat plasma by liquid chromatography-tandem mass spectrometry: Application to preclinical pharmacokinetic drug-drug interaction analysis.

        El Hamd MA, Wada M, Ikeda R, Kawakami S, Kuroda N, Nakashima K

        Biomedical Chromatography 29: 325-327, 2015.


[15] 化学発光HPLCによる血漿中パラコート及びジクワットの同時定量.

        新藤敬梧,岸川直哉,大山 要,黒田直敬

        分析化学 64: 581-587, 2015.


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2014 [PDF]

[1] Rapid determination of isoamyl nitrite in pharmaceutical preparations by flow injection analysis with on-line UV irradiation and luminol chemiluminescence detection.
    Kishikawa N, Kondo N, Amponsaa-Karikari A, Kodamatani H, Ohyama K, Nakashima K, Yamazaki S, Kuroda N
    Luminescence 29 (1): 8-12, 2014.

[2] Determination of the ratio between mercaptalbumin and nonmercaptalbumin by HPLC with fluorescence probe specifically binding to albumin.
    Ohyama K, Kishikawa N, Matsuo A, Imazato T, Ueki Y, Wada M, Nakashima K, Kuroda N
    Journal of Pharmceutical and Biomedical Analysis 88: 170-103, 2014.

[3] Chromatographic determination of low-molecular mass unsaturated aliphatic aldehydes with peroxyoxalate chemiluminescence detection after fluorescence labeling with 4-(N,N-dimethylaminosulfonyl)-7-hydrazino-2,1,3- benzoxadiazole.
    Ali MF, Kishikawa N, Ohyama K, Mohamed HA, Abdel-Wadood HM, Mahmoud AM, Imazato T, Ueki Y, Wada M, Kuroda N

    Journal of Chromatography B 953-954: 147-152, 2014.

[4] Evaluation of lophine derivatives as L-012 (luminol analog)-dependent chemiluminescence enhancers for measuring horseradish peroxidase and H2O2.
    Ichibangase T, Ohba Y, Kishikawa N, Nakashima K, Kuroda N
    Luminescence 29(2) 118-121, 2014.

[5] Determination of 4-hydroxy-2-nonenal in serum by high-performance liquid chromatography with fluorescence detection after pre-column derivatization using 4-(N,N-dimethylaminosulfonyl)-7-hydrazino-2,1,3-benzoxadiazole.
    Imazato T, Shiokawa A, Kurose Y, Katou Y, Kishikawa N, Ohyama K, Ali MF, Ueki Y, Maehata E, Kuroda N

    Biomedical Chromatogrphy 28(6): 891-894, 2014.


[6] Fluorescence derivatization method for sensitive chromatographic determination of zidovudine based on the Huisgen reaction.
    Maeda Y, Kishikawa N, Ohyama K, Wada M, Ikeda R, Kuroda N
    Journal of Chromatography A 1355: 206-210, 2014.

[7] Analytical method for lipoperoxidation relevant reactive aldehydes in human sera by high-performance liquid chromatography-fluorescence detection.
    El-Maghrabey MH, Kishikawa N, Ohyama K, Kuroda N
    Analytical Biocehmistry 464: 36-42, 2014.

[8] Preparation and characterization of surfactin-modified silica stationary phase for reversed-phase and hydrophilic interaction liquid chromatography.

    Ohyama K, Inoue Y, Kishikawa N, Kuroda N
    Journal of Chromatography A 1371: 257-260, 2014.

[9] Determination of folates by HPLC-chemiluminescence using a ruthenium(II)-cerium(IV) system, and its application to pharmaceutical preparations and supplements.
    Ikeda R, Ichiyama K, Tabuchi N, Wada M, Kuroda N, Nakashima K
    Luminescence 29 (7): 824-830, 2014.

[10] In vitro screening of Fe2+-chelating effect by a Fenton's reaction-luminol chemiluminescence system.
    Wada M, Komatsu H, Ikeda R, Aburjai TA, Alkhalil SM, Kuroda N, Nakashima K    
    Luminescence, 29 (7): 955-958, 2014.

[11] Quantitation of sulfur-containing amino acids, homocysteine, methionine and cysteine in dried blood spot from newborn baby by HPLC-fluorescence detection.
    Wada M, Komatsu H, Ikeda R, Aburjai TA, Alkhalil SM, Kuroda N, Nakashima K
    Biomedical Chromatography 28 (6): 810-814, 2014.

[12] Analytical techniques for the determination of biologically active quinones in biological and environmental samples.
    Kishikawa N, Kuroda N
    Journal of Pharmacytical and Biomedical Analysis 87: 261-270, 2014.

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2013 [PDF]



[1] A simple and rapid chemiluminescence assay for on-site analysis of paraquat using a portable luminometer   

    Kishikawa, Naoya; Higuchi, Sho; Ohyama, Kaname; Nakashima, Kenichiro; Kuroda, Naotaka   

    Forensic Toxicology, 31(2), pp.301-306; 2013


[2] Chromatographic determination of aliphatic aldehydes in human serum after pre-column derivatization using 2,2'-furil, a novel fluorogenic reagent   
    Fathy Bakr Ali, Marwa; Kishikawa, Naoya; Ohyama, Kaname; Abdel-Mageed Mohamed, Horria; Mohamed Abdel-Wadood, Hanaa; Mohamed Mohamed, Ashraf; Kuroda,     Naotaka   
    Journal of Chromatography A, 1300, pp.199-203; 2013


[3] HPLC Determination of Chlorpropamide in Human Serum by Fluorogenic Derivatization Based on the Suzuki Coupling Reaction with Phenylboronic Acid   

    Kishikawa, Naoya; Hammad, Sherin Farouk; Ohyama, Kaname; Kubo, Kimiko; Mabrouk, Mokhtar Mohamed; Nakashima, Kenichiro; Kuroda, Naotaka   

    Chromatographia, 76(11-12), pp.703-706; 2013


[4] A novel lophine-based fluorescence probe and its binding to human serum albumin   

    Kishikawa, Naoya; Ohyama, Kaname; Saiki, Akane; Matsuo, Aya; Ali, Marwa Fathy Bakr; Wada, Mitsuhiro; Nakashima, Kenichiro; Kuroda, Naotaka   

    Analytica Chimica Acta, 780, pp.1-6; 2013


[5] Characterization and Comparison of Methacrylic Acid with 2-Acrylamido-2-methyl-1-propanesulfonic Acid in the Preparation of Monolithic Column for Capillary Electrochromatography   

    Horiguchi, Daisuke; Ohyama, Kaname; Masunaga, Tomoko; Fujita, Yoshiko; Ali, Marwa Fathy Bakr; Kishikawa, Naoya; Kuroda, Naotaka   

    Journal of Chromatographic Science, 51(5), pp.425-429; 2013


[6] Immune Complexome Analysis   

    Ohyama, Kaname; Kuroda, Naotaka   

    Advances in Clinical Chemistry, 60, pp.129-141; 2013


[7] Optimization of separation and digestion conditions in immune complexome analysis   

    Baba, Miyako; Ohyama, Kaname; Kishikawa, Naoya; Kuroda, Naotaka   

    Analytical Biochemistry, 443(2), pp.181-186; 2013


[8] Development and validation of the first assay method coupling liquid chromatography with chemiluminescence for the simultaneous determination of menadione and its thioether conjugates in rat plasma
    Elgawish, Mohamed Saleh; Shimomai, Chikako; Kishikawa, Naoya; Ohyama, Kaname; Nakashima, Kenichiro; Kuroda, Naotaka
    Chemical Research in Toxicology, 26(9), pp. 1409-1417; 2013

[9] Simultaneous determination of amphetamine-type stimulants in abusers’ hair: clinical usefulness of hair analysis in prehospitalization for abusers.
    Wada, Mitsuhiro; Sugimoto, Yuki; Crabtree, Brian L; Evans, Cynthia; Montgomery, John H; Ikeda, Rie; Kuroda, Naotaka; Nakashima, Kenichiro
    Forensic Toxicology, 31 (1), pp. 2-8, 2013

[10] Simultaneous determination of homocysteine, methionine and cysteine in maternal plasma after delivery by HPLC-fluorescence detection with DBD-F as a label
    Wada, Mitsuhiro; Hirose, Maki; Kuroki, Mana; Ikeda, Rie; Sekitani Yui; Takamura, Noboru; Kuroda, Naotaka; Nakashima, Kenichiro 
    BiomedicaL Chromatography,  27 (6), 708?713; 2013

[11] Warning against co-administration of 3,4-methylenedioxymethamphetamine (MDMA) with methamphetamine from the perspective of pharmacokinetic and pharmacodynamic evaluations in rat brain
    Fuchigami, Yuki; Ikeda, Rie; Kuzushima, Miki; Wada, Mituhiro, Kuroda, Naotaka; Nakashima, Kenichiro
    European Journal of Pharmaceutical Sciences, 49 (1): 57-64, 2013.

[12] Interaction study of acetylcholinesterase inhibitors on pharmacokinetics of memantine in rat plasma by HPLC-fluorescence method
    Hassan, Mohamed G; Ikeda, Rie; Wada, Mitsuhiro; Kuroda, Naotaka; Abdel-Wadood, Hanaa M; Mohamed, Horria A; Nakashima, Kenichiro
    BiomedicaL Chromatography, 27 (12): 1685-1689, 2013. 

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2012 [PDF] 



[1] Microplate analytical method for quinones by pulse photo-irradiation and chemiluminescence detection   
    Elgawish, Mohamed Saleh; Shimomai, Chikako; Kishikawa, Naoya; Ohyama, Kaname; Nakashima, Kenichiro; Kuroda, Naotaka   
    Analyst, 137(20), pp.4802-4808; 2012

[2] Serum immune complex containing thrombospondin-1: a novel biomarker for early rheumatoid arthritis  
    Ohyama, Kaname; Kawakami, Atsushi; Tamai, Mami; Baba, Miyako; Kishikawa, Naoya; Kuroda, Naotaka   
    Annals of the Rheumatic Diseases, 71(11), pp.1916-1917; 2012


[3] Proteomic Approaches to Profiling the Humoral Immune Response and Identifying Disease-Associated Antigens   
    Ohyama, Kaname; Kuroda, Naotaka   
    Biological and Pharmaceutical Bulletin, 35(9), pp.1409-1412; 2012


[4] Challenge of Mass Spectrometry toward the Elucidation of Life Phenomena: Foreword   
    Kuroda, Naotaka   
    Biological and Pharmaceutical Bulletin, 35(9), p.1392; 2012


[5] Development of a novel method for monitoring the antioxidative effect of ascorbic acid in rat blood   
    Wada, Mitsuhiro; Kira, Megumi; Nakaji, Yosuke; Ikeda, Rie; Kuroda, Naotaka; Nakashima, Kenichiro  
    Food Chemistry, 134(1), pp.546-552; 2012


[6] Determination of glyoxylic acid in urine by liquid chromatography with fluorescence detection, using a novel derivatization procedure based on the Petasis reaction   
    Chihara, Kohki; Kishikawa, Naoya; Ohyama, Kaname; Nakashima, Kenichiro; Kuroda, Naotaka   
    Analytical and Bioanalytical Chemistry, 403(9), pp.2765-2770; 2012


[7] Toxicoproteomic analysis of a mouse model of nonsteroidal anti-inflammatory drug-induced gastric ulcers   
    Ohyama, Kaname; Shiokawa, Akina; Ito, Kosei; Masuyama, Ritsuko; Ichibangase, Tomoko; Kishikawa, Naoya; Imai, Kazuhiro; Kuroda, Naotaka   
    Biochemical and Biophysical Research Communications, 420(1), pp.210-215; 2012


[8] 蛍光・化学発光反応に基づく高選択的検出法の開発と生体分析への応用   
    岸川, 直哉   
    分析化学, 61(7), pp.583-590; 2012

[9] Simultaneous determination of five polyether ionophores using liquid chromatography with one-step fluorescent derivatization
    Inoue, Koichi; Miura, Yukiko; Suzuki, Misato; Kishikawa, Naoya; Hino, Tomoaki, Kuroda, Naotaka; Oka Hisao
    Analytical Sciences, 28, pp. 175-178; 2012


[10] Determination of memantine in rat plasma by HPLC fluorescence method and its application to study of the pharmacokinetic interaction between memantine and methazolamide
    Hassan, Mohamed G;  Emara, Kamia M; Mohamed, Horria A; Abdel-Wadood Hanaa M; Ikeda, Rie; Wada, Mituhiro; Kuroda, Naotaka; Nakashima, Kenichiro
    BiomedicaL Chromatography, 26, pp. 214-219; 2012

[11] Evaluation of hair roots for detection of methamphetamine and 3, 4-methylenedioxymethamphetamine abuse by use of an HPLC?chemiluminescence method.
    Wada, Mituhiro; Ochi, Yuko; Nogami, Kumi; Ikeda, Rie; Kuroda, Naotaka; Nakashima, Kenichiro
    Analytical and Bioanalytical Chemistry, 403, pp. 2569?2576; 2012

[12] Simultaneous determination of N-benzylpiperazine and 1-(3-trifluoromethylphenyl)piperazine in rat plasma by HPLC-fluorescence detection and its
application to monitoring of these drugs

    Wada, Mitsuhiro; Yamahara, Kozue; Ikeda, Rie; Kikura-Hanajiri, Ruri; Kuroda, Naotaka; Nakashima, Kenichiro  
    BiomedicaL Chromatography, 26, pp. 21-25; 2012

[13] Determination of methamphetamine in neonatal hair and meconium samples: estimation of fetal drug abuse during pregnancy.
    Wada, Mitsuhiro; Sugimoto, Yuki; Ikeda, Rie; Isono, Kazutomo; Kuroda, Naotaka; Nakashima, KenichiroWada M, Sugimoto Y, Ikeda R, Isono K, Kuroda N, Nakashima K:
    Forensic Toxicology, 30, pp. 80-83; 2012


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2011 [PDF] 



[1] Effects of Temperature and Mobile Phase Condition on Chiral Recognition of Poly(l-phenylalanine) Chiral Stationary Phase   
    Ohyama, Kaname; Oyamada, Kana; Kishikawa, Naoya; Wada, Mitsuhiro; Ohba, Yoshihito; Nakashima, Kenichiro; Kuroda, Naotaka   
    Chromatographia, 74(5-6), pp.467-470; 2011


[2] 4-Carbomethoxybenzaldehyde as a highly sensitive pre-column fluorescence derivatization reagent for 9,10-phenanthrenequinone.   
    Kishikawa, Naoya; Nakao, Maiko; Elgawish, Mohamed Saleh; Ohyama, Kaname; Nakashima, Kenichiro; Kuroda, Naotaka   
    Talanta, 85(1), pp.809-812; 2011


[3] Selective chemiluminescence method for monitoring of vitamin K homologues in rheumatoid arthritis patients.   
    Ahmed, Sameh; Kishikawa, Naoya; Ohyama, Kaname; Imazato, Takahiro; Ueki, Yukitaka; Kuroda, Naotaka   
    Talanta, 85(1), pp.230-236; 2011


[4] Labeling of alprenolol with fluorescent aryl iodide as a reagent based on Mizoroki-Heck coupling reaction.   
    Kishikawa, Naoya; Ohkuma, Mizuho; Wada, Mitsuhiro; Ohyama, Kaname; Ikeda, Rie; Nakashima, Kenichiro; Kuroda, Naotaka   
    Journal of Chromatography. A, 1218(20), pp.3002-3006; 2011


[5] Selective determination of ubiquinone in human plasma by HPLC with chemiluminescence reaction based on the redox cycle of quinone.   
    Kishikawa, Naoya; Ohkubo, Nobuhiro; Ohyama, Kaname; Nakashima, Kenichiro; Kuroda, Naotaka   
    Analytical and bioanalytical chemistry, 400(2), pp.381-385; 2011


[6] HPLC determination of methylphenidate and its metabolite, ritalinic acid, by high-performance liquid chromatography with peroxyoxalate chemiluminescence detection.
    Wada, Mitsuhiro; Abe, Keisuke; Ikeda, Rie; Kikura-Hanajiri, Ruri; Kuroda, Naotaka; Nakashima, Kenichiro   
    Analytical and Bioanalytical Chemistry, 400(2), pp.387-393; 2011


[7] HPLC-UV method development for fentanyl determination in rat plasma and its application to elucidate pharmacokinetic behavior after i.p. administration to rats.  
    Almousa, Ahmed A; Ikeda, Rie; Wada, Mitsuhiro; Kuroda, Naotoka; Hanajiri, Ruri-Kikura; Nakashima, Kenichiro  
    Journal of Chromatography B, 879(27), pp.2941-2944; 2011

[8] Pharmacodynamic interactions between MDMA and concomitants in MDMA tablets on extracellular dopamine and serotonin in the rat brain.   
    Ikeda, Rie; Igari, Yoshiko; Fuchigami, Yuki; Wada, Mitsuhiro; Kuroda, Naotaka; Nakashima, Kenichiro   
    European Journal of Pharmacology, 660(2-3), pp.318-325; 2011

[9] HPLC determination of methylphenidate and its metabolite, ritalinic acid, by high-performance liquid chromatography with peroxyoxalate chemiluminescence detection.   
    Wada, Mitsuhiro; Abe, Keisuke; Ikeda, Rie; Kikura-Hanajiri, Ruri; Kuroda, Naotaka; Nakashima, Kenichiro   
    Analytical and Bioanalytical Chemistry, 400(2), pp.387-393; 2011


[10] Immune complexome analysis of serum and its application in screening for immune complex antigens in rheumatoid arthritis
    Ohyama, Kaname; Ueki, Yukitaka; Kawakami, Atsushi; Kishikawa, Naoya; Tamai, Mami; Osaki, Makoto; Kamihira, Shimeru; Nakashima, Kenichiro; Kuroda, Naotaka
    Clinical Chemistry, 57 (6), pp. 905-909; 2011


[11] Suitability of TBA method for the evaluation of the oxidative effect of non-water-soluble rosemary extracts.
    Wada, Mitsuhiro; Nagano, Minori; Kido, Hirotsugu; Ikeda, Rie; Kuroda, Naotaka; Nakashima, Kenichiro
    Journal of  Oleo Science, 60 (11), pp. 579-584, 2011

[12] Semi-micro flow injection analysis method for evaluation of quenching effect of health foods or food additive antioxidants on peroxynitrite.
    Wada, Mitsuhiro; Kira, Megumi; Kido, Hirotsugu; Ikeda, Rie; Kuroda, Naotaka; Nishigaki, Toshiaki; Nakashima, Kenichiro  
    Luminescence 26 (3): 191-195, 2011

[13] Quantification of vitamin K in foods. In Fortified Foods with Vitamins.
    Ahmed, Sameh; Kishikawa, Naoya; Ohyama, Kaname; Kuroda, Naotaka
    Analytical Concepts to Assure Better and Safer Products (Rychlik Meds; Wiley & Sons, New York), pp. 237-256, 2011


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2010 [PDF] 




[1] Peroxyoxalate chemiluminescence detection for the highly sensitive determination of fluorescence-labeled chlorpheniramine with Suzuki coupling reaction.   

    Adutwum, Lawrence Asamoah; Kishikawa, Naoya; Ohyama, Kaname; Harada, Shiro; Nakashima, Kenichiro; Kuroda, Naotaka   

    Analytical and Bioanalytical Chemistry, 398(2), pp.823-829; 2010


[2] A toxicoproteomic study on cardioprotective effects of pre-administration of docetaxel in a mouse model of adriamycin-induced cardiotoxicity.   

    Ohyama, Kaname; Tomonari, Mari; Ichibangase, Tomoko; To, Hideto; Kishikawa, Naoya; Nakashima, Kenichiro; Imai, Kazuhiro; Kuroda, Naotaka   

    Biochemical Pharmacology, 80(4), pp.540-547; 2010


[3] Determination of 9, 10-phenanthrenequinone in airborne particulates by High-Performance Liquid Chromatography with post-column fluorescence derivatization using 2-aminothiophenol.   

    Kishikawa, Naoya; Nakashima, Hajime; Ohyama, Kaname; Nakashima, Kenichiro; Kuroda, Naotaka   

    Talanta, 81(4-5), pp.1852-1855; 2010


[4] Study on the Timing of Degassing for Reproducible Preparation of Polymer-Based Monolithic Columns   

    Ohyama, Kaname; Sueyoshi, Tomoyuki; Kishikawa, Naoya; Nakashima, Kenichiro; Kuroda, Naotaka   

    Chromatographia, 71(9-10), pp.971-973; 2010


[5] Evaluation of chemiluminescence reagents for selective detection of reactive oxygen species.   

    Yamaguchi, Shinya; Kishikawa, Naoya; Ohyama, Kaname; Ohba, Yoshihito; Kohno, Maiko; Masuda, Toshinobu; Takadate, Akira; Nakashima, Kenichiro; Kuroda, Naotaka   

    Analytica Chimica Acta, 665(1), pp.74-78; 2010


[6] Automated analysis of the serum antioxidative activities against five different reactive oxygen species by sequential injection system with a chemiluminescence detector.   

    Kishikawa, Naoya; Ohyama, Kaname; Yao, Junko; Miyamoto, Aoi; Imazato, Takahiro; Ueki, Yukitaka; Nakashima, Kenichiro; Maehata, Eisuke; Kuroda, Naotaka   

    Clinica Chimica Acta, 411(15-16), pp.1111-1115; 2010


[7] Adamantyl-functionalized polymer monolith for capillary electrochromatography.   

    Ohyama, Kaname; Fukahori, Yuki; Nakashima, Kenichiro; Sueyoshi, Tomoyuki; Kishikawa, Naoya; Kuroda, Naotaka   

    Journal of Chromatography. A, 1217(9), pp.1501-1505; 2010


[8] Enhancement of peroxyoxalate chemiluminescence intensity by surfactants and its application to detect detergent.   

    Wada, Mitsuhiro; Abe, Keisuke; Ikeda, Rie; Harada, Shiro; Kuroda, Naotaka; Nakashima, Kenichiro   

    Talanta, 81(3), pp.1133-1136; 2010


[9] キノンの選択的蛍光・化学発光定量法の開発と環境・生体分析への応用   

    岸川, 直哉   

    薬学雑誌, 130(10), pp.1319-1324; 2010


[10] キノンの選択的化学発光検出法とその臨床化学的応用   

    黒田, 直敬; 岸川, 直哉; 大山, 要   

    臨床化学, 39(1), pp.15-21; 2010


[11] Analytical methods for abused drugs in hair and their applications.
    Wada, Mitsuhiro; Ikeda, Rie; Kuroda, Naotaka; Nakashima, Kenichiro

    Analytical and Bioanalytical Chemistry, 397, pp. 1039-1067; 2010

[12] π-π Active stationary phases immobilized with organic dyes and their analogues for high-performance liquid chromatography and capillary electrochromatography.
    In Chromatography
    Ohyama, Kaname; Nakashima, Kenichiro; Wada, Mitsuhiro; Kishikawa, Naoya; Kuroda, Naotaka
    Types, Techniques and Methods (Quintin TJ eds; Nova Science Publisher, New York) pp. 443-456, 2010

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2009 [PDF]  



[1] Investigation of Novel Peptide Chiral Selectors Prepared by Solid-Phase Synthesis with a tert-Butoxycarbonyl Amino Acid   
    Ohyama, Kaname; Oyamada, Kana; Kishikawa, Naoya; Arakawa, Miyuki; Ohba, Yoshihito; Kamino, Masahiro; Wada, Mitsuhiro; Nakashima, Kenichiro; Kuroda, Naotaka   
    Chromatographia, 70(9-10), pp.1501-1504; 2009


[2] An ultrasensitive and highly selective determination method for quinones by high-performance liquid chromatography with photochemically initiated luminol chemiluminescence.   
    Ahmed, Sameh; Kishikawa, Naoya; Ohyama, Kaname; Maki, Toshihide; Kurosaki, Hiromasa; Nakashima, Kenichiro; Kuroda, Naotaka   
    Journal of Chromatography A, 1216(18), pp.3977-3984; 2009


[3] Chemiluminescence assay for quinones based on generation of reactive oxygen species through the redox cycle of quinone.   
    Kishikawa, Naoya; Ohkubo, Nobuhiro; Ohyama, Kaname; Nakashima, Kenichiro; Kuroda, Naotaka   
    Analytical and Bioanalytical Chemistry, 393(4), pp.1337-1343; 2009


[4] Fluorogenic derivatization of aryl halides based on the formation of biphenyl by Suzuki coupling reaction with phenylboronic acid.   
    Kishikawa, Naoya; Kubo, Kimiko; Hammad, Sherin Farouk; Mabrouk, Mokhtar Mohamed; Habib, Ahmed; Elfatatry, Hamed; Ohyama, Kaname; Nakashima, Kenichiro; Kuroda, Naotaka   
    Journal of Chromatography. A, 1216(40), pp.6873-6876; 2009


[5] Evaluation of Organic Environmental Pollutants Detected in Human Milk   
    Kishikawa, Naoya; Kuroda, Naotaka   
    Journal of Health Science, 55(1), pp.1-10; 2009


[6] Determination of halofantrine and its main metabolite desbutylhalofantrine in rat plasma by high-performance liquid chromatography with on-line UV irradiation and peroxyoxalate chemiluminescence detection.
    Amponsaa-Karikari, Abena; Kishikawa, Naoya; Ohyama, Kaname; Nakashima, Kenichiro; Kuroda, Naotaka     
    Biomedical Chromatography, 23 (1), pp. 101-106; 2009


[7] Selective determination of doxorubicin and doxorubicinol in rat plasma by HPLC with photosensitization reaction followed by chemiluminescence detection. 
    Ahmed, Sameh; Kishikawa, Naoya; Ohyama, Kaname; Wada, Mitsuhiro; Nakashima, Kenichiro; Kuroda, Naotaka     
    Talanta. 78 (1), pp. 94-100, 2009


[8] Novel mixed-mode stationary phases for capillary electrochromatography.
    Ohyama, Kaname; Kuroda, Naotaka
    Advances in
chromatography vol. 47, ed. by E. Grushka and N. Grinberg, Taylor & Francis, Chapter 4, pp127-163, 2009

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2008 [PDF]



Simultaneous determination of mycophenolic acid and its acyl and phenol glucuronide metabolites in human serum by capillary zone electrophoresis   Ohyama, Kaname; Kishikawa, Naoya; Nakagawa, Hiroo; Kuroda, Naotaka; Nishikido, Masaharu; Teshima, Mugen; To, Hideto; Kitahara, Takashi; Sasaki, Hitoshi

Journal of Pharmaceutical and Biomedical Analysis, 47(1), pp.201-206; 2008



Sensitive HPLC-fluorescence detection of morphine labeled with DIB-Cl in rat brain and blood microdialysates and its application to the preliminarily study of the pharmacokinetic interaction between morphine and diclofenac.   

Wada, Mitsuhiro; Yokota, Chiaki; Ogata, Yasuhiro; Kuroda, Naotaka; Yamada, Hideyuki; Nakashima, Kenichiro   

Analytical and Bioanalytical Chemistry, 391(3), pp.1057-1062; 2008



Preparation and characterization of poly(l-phenylalanine) chiral stationary phases with varying peptide length.   

Ohyama, Kaname; Oyamada, Kana; Kishikawa, Naoya; Ohba, Yoshihito; Wada, Mitsuhiro; Maki, Toshihide; Nakashima, Kenichiro; Kuroda, Naotaka    Journal of Chromatography A, 1208(1-2), pp.242-245; 2008



A simple and rapid CZE method for the analysis of mycophenolic acid and its phenol glucuronide metabolite in human serum.

Ohyama, Kaname; Kinoshita, Naoyuki; Kishikawa, Naoya; Kuroda, Naotaka

Electrophoresis, 29 (17), pp. 3658-3664, 2008


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2007 [PDF] 




Quasi-simultaneous determination of antioxidative activities against superoxide anion and nitric oxide by a combination of sequential injection analysis and flow injection analysis with chemiluminescence detection
Miyamoto Aoi, Nakamura Kuniko, Kishikawa Naoya, Ohba Yoshihito, Nakashima Kenichiro, Kuroda Naotaka
Analytical and Bioanalytical Chemistry, 388, pp. 1809-1814; 2007


Precolumn fluorescence labeling method for simultaneous determination of hydroxyzine and cetirizine in human serum
Hammad Sherin F, Mabrouk Mokhtar M, Habib Ahmed, Elfatatry Hamed, Kishikawa Naoya, Nakashima Kenichiro, Kuroda Naotaka
Biomedical Chromatography, 21, pp. 1030-1035; 2007


Determination of vitamin K homologues by high-performance liquid chromatography with on-line photoreactor and peroxyoxalate chemiluminescence detection
Ahmed Sameh, Kishikawa Naoya, Nakashima Kenichiro, Kuroda Naotaka
Analytica Chimica Acta, 591, pp. 148-154; 2007


Chemiluminescent screening of quenching effects of natural colorants against reactive oxygen species: Evaluation of grape seed, monascus, gardenia and red radish extracts as multi-functional food additives
Wada Mitsuhiro, Kido Hirotsugu, Ohyama Kaname, Ichibangase Tomoko, Kishikawa Naoya, Ohba Yoshihito, Nakashima Mihoko, Kuroda Naotaka, Nakashima Kenixhiro
Food Chemistry,  101, pp. 980-986; 2007


A sensitive semi-micro column HPLC-peroxyoxalate chemiluminescence detection with column switching system for determination of MDMA related compounds in hair
Nakamura Shinichi, Wada Mitsuhiro, Crabtree Brian L, Reeves Patricia M, Montgomery John H, Byrd H Joseph, Harada Shiro, Kuroda Naotaka, Nakashima Kenichiro
Analytical and Bioanalytical Chemistry, 387, pp. 1983-1990; 2007.


Determination of aromatic compounds by high-performance liquid chromatography with on-line photoreactor and peroxyoxalate chemiluminescence detection
Ihara Ayuko, Kishikawa Naoya, Wada Mitsuhiro, Ohba Yoshihito, Nakashima Kenichiro, Kuroda Naotaka
Luminescence, 22, pp. 567-574; 2007


Capillary electrochromatography of charged biomolecules with mixed-mode stationary phases
Ohyama Kaname, Kuroda Naotaka
Journal of Liquid Chromatography & Related Technologies, 30, pp. 833-851; 2007


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2006 [PDF] 



Sequential injection analysis with chemiluminescence detection for the antioxidative activity against singlet oxygen.

Miyamoto Aoi, Nakamura Kuniko, Ohba Yoshihito, Kishikawa Naoya, Nakashima Kenichiro, Kuroda Naotaka

Analytical  Sciences,  22, pp. 73-76; 2006


Study on immunocapture-chemiluminescence assay of lipase activity in a biological sample.

Ichibangase Tomoko, Hamabe Chie, Ohba Yoshihito, Kishikawa Naoya, Nakashima Kenichiro, Kayamori Yuzo, Kang Dongchon, Hamasaki Naotaka, Kuroda Naotaka

Luminescence, 21, pp. 62-66; 2006



Quantification of MDMA and MDA in abusers’ hair samples by semi-micro column HPLC with fluorescence detection

Nakamura Shinichi, Tomita Mamoru, Wada MItsuhiro, Chung Heesun, Kuroda Naotaka, Nakashima Kenichiro

Biomedical Chromatography, 20, pp. 622-627; 2006



Concentration and trend of 9,10-phenanthrenequinone in airborne particulates collected in Nagasaki city, Japan.

Kishikawa Naoya, Nakao Maiko, Ohba Yoshihito, Nakashima Kenichiro, Kuroda Naotaka

Chemosphere, 64, pp. 834-838, 2006



Determination of haloperidol and reduced haloperidol in human serum by liquid chromatography after fluorescence labeling based on the Suzuki coupling reaction.

Kishikawa Naoya, Hamachi Chiyuki, Imamura Yoshihiro, Ohba Yoshihito, Nakashima Kenichiro, Tagawa Yasuhiro, Kuroda Naotaka

Analytical and Bioanalytical Chemistry, 386,  pp. 719-724; 2006



Selective determination of quinones by high-performance liquid chromatography with on-line post column ultraviolet irradiation and peroxyoxalate chemiluminescence detection.

Ahmed Sameh, Fujii Shuu, Kishikawa Naoya, Ohba Yoshihito, Nakashima Kenichiro, Kuroda Naotaka

Journal of Chromatography A, 1133, pp. 76-82; 2006



Determination of artemisinin in human serum by high-performance liquid chromatography with on-line UV irradiation and peroxyoxalate chemiluminescence detection.

Amponsaa-Karikari, Abena; Kishikawa, Naoya; Ohyama, Kaname; Nakashima, Kenichiro; Kuroda, Naotaka     
Biomedical Chromatography,
20, pp. 1157-1162; 2006



Human biomonitoring of endocrine disrupting chemicals by HPLC methods.

Kishikawa Naoya,  Ohyama Kaname, Kuroda Naotaka

Current Analytical Chemistry, 2, pp. 77-88; 2006



プ ロエンハンサー基質を用いる製剤中のリパーゼ活性の簡易,迅速な化学発光測定

有 馬, 貴美代; 一番ヶ瀬, 智子; 大庭, 義史; 岸川, 直哉; 黒田, 直敬   

分 析化学, 55(5), pp. 307-311; 2006



フ ローインジェクション-ルミノール化学発光検出によるブドウ種子抽出物及びポリフェノール類の活性酸素種消去能評価   

和 田, 光弘; 加藤, 正之; 城戸, 浩胤; 中嶋, 弥穂子; 黒田, 直敬; 中島, 憲一郎   

分 析化学, 55(12), pp. 931-936; 2006



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