研究業績

2002年
<Research article>
H. Yamamoto, P. Zhao, K. Inoue: Origin of two isoprenoid units in a lavandulyl moiety of sophoraflavanone G from Sophora flavescens cultured cells.Phytochemistry, 60(3), 263-267 (2002).

Y. Kitamura, M. Ohata, T. Ikenaga and M. Watanabe M: Responces of anthocyanin- producing and non-producing cell cultures of Glehnia littoralis to  radical generators. Phytochemistry 59, 63-68 (2002).

H. Yamamoto, M. Sha, Y. Kitamura, M. Yamaguchi, N. Katano and K. Inoue: Iridoid biosynthesis: 7-Deoxyloganetic acid 1-O-glucosyltransferase in cultured Lonicera japonica cells. Plant Biotechnology 19, 295-301 (2002).

Y . Kitamura, K. Kubo, L.R. Rahman and T. Ikenaga: Reproduction of Sedum drymarioides, an endangered rare species, by micropropagation. Plant Biotechnology 19, 303-309 (2002).

H. Yamamoto, P. Zhao, K. Yazaki, K. Inoue: Regulation of lithospermic acid B and shikonin production in Lithospermum erythrorhizon cell suspension cultures. Biosci. Chemical & Pharmaceutical Bulletin 50 (8), 1086 - 1090 (2002).

2001年
<Research article>
H. Yamamoto, A. Yatou, K. Inoue: 8-Dimethylallylnaringenin 2'-hydroxylase, the crucial cytochrome P450 monooxygenase for lavandulylated flavanone formation in Sophora flavescens cultured cells. Phytochemistry, in press (2001).

N. Katano, H. Yamamoto, R. Iio, K. Inoue: 7-Deoxyloganin 7-hydroxylase in Lonicera japonica cell cultures. Phytochemistry, 58 (1), 53 - 58 (2001)

H. Yamamoto, A. Yatou, K. Yazaki, H. Hayashi, G. Taguchi, K. Inoue: Increases of secondary metabolite production in various plant cell cultures. Biosci. Biotechnol. Biochem., 65 (4), 853 - 860 (2001).

北村美江:アサの種子の発芽と雌雄異株について, 長崎県生物学会誌, 52, 19-23 (2001).

<Review>

2000年
<Research article>
H. Yamamoto, N. Katano, A. Ooi, K. Inoue: Secologanin synthase which catalyzes the oxidative cleavage of loganin into secologanin is a cytochrome P-450, Phytochemistry, 53 (1), 7-12 (2000).

H. Yamamoto, K. Inoue, S.-M. Li, L. Heide: Geranylhydroquinone 3"-hydroxylase, a cytochrome P-450 monooxygenase from Lithospermum erythrorhizon cell suspension cultures, Planta, 210 (2), 312-317 (2000).

H. Yamamoto, K. Yazaki, K. Inoue: Simultaneous analysis of shikimate-derived secondary metabolites in Lithospermum erythrorhizon cell suspension cultures by high-performance liquid chromatography, Journal of Chromatography B: Biomedical Sciences and Applications, 738 (1), 3-15 (2000).

H. Yamamoto, K. Yazaki, K. Inoue: Production of caffeic acid oligomers in Lithospermum erythrorhizon cell suspension cultures. Phytochemistry, 53 (6), 651-657 (2000).

H. Hayashi, N. Hosono, M. Kondo, N. Hiraoka, Y. Ikeshiro, M. Shibano, G. Kusano, H. Yamamoto, T. Tanaka, K. Inoue: Phylogenetic relationship of six Glycyrrhiza species based on rbcL sequences and chemical constituents, Biol. Pharm. Bull., 23 (5), 602-606 (2000).

H. Yamamoto, M. Senda, K. Inoue: Flavanone 8-dimethylallyltransferase in Sophora flavescens cell suspension cultures. Phytochemistry, 54 (7), 649-655 (2000).

<Review>
富永義則,北村美江,田中 隆:シーボルトの処方箋,薬用植物研究,薬用植物栽培研究会編,23, 62 - 74 (2000)

北村美江:酵素のいらない生合成,ファルマシア 2, 147 - 148 (2000).

1999年
<Research article>
H. Yamamoto, N. Katano, A. Ooi, K. Inoue: Transformation of loganin and 7-deoxyloganin into secologanin by Lonicera japonica cell suspension cultures, Phytochemistry, 50, 417-422, (1999).

H. Yamamoto, K. Yazaki, H. Hayashi, G. Taguchi, A. Yatou, K. Inoue: Effects of cork tissues on the production of secondary metabolites in various plant cell cultures, Recent Research Developments in Biotechnology and Bioengineering, 2, 273-281 (1999).

A. Mitra, Y. Kitamura , M.J. Gasson, A. Narbad, A.J. Parr, J. Payne,M.J.C. Rhodes, C. Sewter, N. J. Walton: 4-hydroxycinnamoyl-CoA hydratase/lyase (HCHL) - an enzyme of phenylpropanoid chain cleavage from Pseudomonas. Archiv. Biochem. Biophys. 365, 10-16 (1999)

A. Mitra, Y. Kitamura, M. J. Mayer, A. J. Michael, A. Narbard, A. J. Parr, N. J. Walton: p-Hydroxycinnamoyl CoA hydratase/lyase (HCHL) - a Psudomonas enzyme expressed in hairy root cultures of Datura stramonium. Biochemical Society Transactions 27, 51 (1999).

北村美江:薬用植物とそれに関わる生物たち 1.トロパンアルカロイド生産植物とカメムシ. 長崎県生物学会誌 50, 30-33 (1999).

<Review>
T. Muranaka, Y. Kitamura, T. Ikenaga: Genetic transformation of Duboisia species. Biotechnology in Agriculture and Forestry, Vol.45, Transgenic Medicinal Plants (ed. by Y. P. S. Bajaj) pp.117-132, 1999, Springer-Verlag Berlin Heidelberg.

Y. Kitamura, M. Ohata, T. Ikenaga, M. Watanabe: Different responces between anthocyanin-producing and non-producing cell cultures of Glehnia littoralis to stress. Plant Biotechnology and In Vitro Biology in the 21st Century Vol. 36 pp.503-506, 1999, Kluwer Academic Publisher.

北村美江:江戸時代の薬園ー薬用植物園の基盤づくりー.長崎薬学史、長崎大学薬学部編 pp16-20、1999.