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2018

Stereoselective Synthesis of the Right-hand Cores of 16-Methylated Oxazolomycins
Eto, Kohei; Ishihara, Jun; Hatakeyama, Susumi
Tetrahedron, 2018, 74 (7), 711-719.

2017

Stereoselective Construction of Entire Diastereomeric Stereotetrads Based on an Asymmetric Morita–Baylis–Hillman Reaction
Yoshimura, Hikaru; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi
Eur. J. Org. Chem., 2017, 19, 2719–2729.

Ionic Liquid-Mediated Hydrofluorination of o-Azaxylylenes Derived from 3-Bromooxindoles
Mizuta, Satoshi; Otaki, Hiroki; Kitagawa, Ayako; Kitamura, Kanami; Morii, Yuki; Ishihara, Jun; Nishi, Kodai; Hashimoto, Ryo; Usui, Toshiya; Chiba, Kenya
Org. Lett., 2017, 19 (10), 2572–2575.

Concise Formation of Spirocyclic Compounds for Marine Phycotoxins
Ishihara, Jun; Tojo, Shingo; Makino, Takuya; Sekiya, Hiroshi; Tanabe, Akiko, Shiraishi, Mitsutaka, Murai, Akio; Hatakeyama, Susumi 
Heterocycles, 2017, 95 (1), 422-444.

Enantioselective Protecting-Group-Free Synthesis of (+)-9,10-Dihydroecklonialactone B
Yassen, Asmaa Said Ali; Ishihara, Jun; Hatakeyama, Susumi
Heterocycles, 2017, 94 (1), 59-63.

2015

Unified Synthesis of Tirandamycins and Streptolydigins
Yoshimura, Hikaru; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi
Chemical Communications, 2015, (51), 17004–17007.

Total Synthesis of (−)-N-Methylwelwitindolinone C Isothiocyanate Based on a Pd-Catalyzed Tandem Enolate Coupling Strategy
Komine, Keita; Nomura, Yusuke; Ishihara, Jun; Hatakeyama, Susumi
Organic Letters, 2015, 17 (15), 3918–3921.

Acid Template-Catalyzed Asymmetric Diels-Alder Reaction
Ishihara, Jun; Nakadachi, Shino; Watanabe, Yuki; Hatakeyama, Susumi
Journal of Organic Chemistry, 2015, 80 (4), 2037-2041.

Stereoselective Approach toward Ophiodilactones Based on an Intramolecular [2+2] Cycloaddition Reaction
Matsubara, Takaaki; Ishihara, Jun; Hatakeyama, Susumi
Heterocycles, 2015, 90 (1), 405-424.

2014

Total Synthesis of Marinomycin A Based on a Direct Dimerization Strategy
Nishimaru, Tatsuya; Kondo, Masashi; Takeshita, Kimito; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi
Angewandte Chemie, International Edition, 2014, 53, 8459-8462.

Total Synthesis of Oxazolomycins
Jun Ishihara; Susumi Hatakeyama
The Chemical Record, 2014, 14 (4), 663-677.

The Absolute Configuration for Inthomycin C: Revision of Previously Published Work with a Reinstatement of the (3R)-Configuration for (-)-Inthomycin C
Hale, Karl J.; Hatakeyama, Susumi; Urabe, Fumiya; Ishihara, Jun; Manaviazar, Soraya; Grabski, Milosz; Maczka, Maciej
Organic Letters, 2014, 16 (13), 3536-3539.

Total Synthesis of (-)-Dihydrosporothriolide Utilizing an Indium-Mediated Reformatsky-Claisen Rearrangement
Ishihara, Jun; Tsuru, Hiroaki; Hatakeyama, Susumi
Journal of Organic Chemistry, 2014, 79 (12), 5908-5913.

Formal [4+1]-Cycloaddition of homopropargyl alcohols to diazo dicarbonyl compounds giving substituted tetrahydrofurans
Urabe, Fumiya; Miyamoto, Shohei; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi
Organic Letters, 2014, 16 (3), 1004–1007.

Total Synthesis of (-)-Ophiodilactone A and (-)-Ophiodilactone B
Matsubara, Takaaki; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi
Angewandte Chemie - International Edition, 2014, 53 (3), 757–760.

Synthesis of Heterocycles Based on Rhodium-Catalyzed C-H Amination
Takahashi, Keisuke; Yamaguchi, Daisuke; Ishihara, Jun; Hatakeyama, Susumi
Synlett, 2014, 25 (1), 133–137.

2013

α-Isocupreine, an enantiocomplementary catalyst of β-isocupreidine
Nakamoto, Yoshito; Urabe, Fumiya; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi
Chemistry - A European Journal, 2013, 19 (38), 12653–12656.

Total synthesis of (-)-cinatrin C1 based on an In(OTf)3-catalyzed Conia-ene reaction
Urabe, Fumiya; Nagashima, Shunsuke; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi
Journal of Organic Chemistry, 2013, 78 (8), 3847–3857.

2012

A new method for the protection of carboxylic acids with a triisopropylsiloxymethyl group
Yoshimura, Hikaru; Eto, Kohei; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi
Chemical & Pharmaceutical Bulletin, 2012, 60 (10), 1334-1339.

Organocatalytic asymmetric syntheses of inthomycins A, B and C
Yoshino, Madoka; Eto, Kohei; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi
Organic & Biomolecular Chemistry, 2012, 10 (40), 8164-8174.

Recent developments in the Reformatsky-Claisen rearrangement
Ishihara, Jun; Hatakeyama, Susumi
Molecules, 2012, 17, 14249-14259.

Stereocontrolled Total Synthesis of (-)-Englerin A
Takahashi, Keisuke; Komine, Keita; Yokoi, Yuichi; Ishihara, Jun; Hatakeyama, Susumi
Journal of Organic Chemistry, 2012, 77 (17), 7364-7370.

Stereoselective synthesis of the fused γ-lactone/δ-lactone core of ophiodilactones
Matsubara, Takaaki; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi
Heterocycles, 2012, 86 (1), 155-158.

Total Synthesis of (-)-Kaitocephalin Based on a Rh-Catalyzed C-H Amination
Takahashi, Keisuke; Yamaguchi, Daisuke; Ishihara, Jun; Hatakeyama, Susumi
Organic Letters, 2012, 14 (6), 1644-1647.

2011

Indium-mediated Reformatsky-Claisen rearrangement
Ishihara, Jun; Watanabe, Yuki; Koyama, Noriko; Nishino, Yukihiro; Takahashi, Keisuke; Hatakeyama, Susumi
Tetrahedron, 2011, 67 (20), 3659-3667.

Organocatalytic asymmetric synthesis of quinine and quinidine
Sarkar, Shaheen M.; Taira, Yuko; Nakano, Ayako; Takahashi, Keisuske; Ishihara, Jun; Hatakeyama, Susumi
Tetrahedron Letters, 2011, 52 (8), 923-927.

Synthetic studies on vitamin D analogs. Part 39. Synthesis of 1-deoxyeldecalcitol, a biologically interesting analog of 1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (eldecalcitol)
Sasaki, Hirotaka; Eto, Kohei; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi; Kubodera, Noboru
Heterocycles, 2011, 83 (6), 1385-1394.

Total synthesis of NW-G01, a cyclic hexapeptide antibiotic, and 34-epi-NW-G01
Shibahara, Setsuya; Matsubara, Takaaki; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi
Organic Letters, 2011, 13 (17), 4700-4703.

Total synthesis of oxazolomycin A
Eto, Kohei; Yoshino, Madoka; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi
Organic Letters, 2011, 13 (19), 5398-5401.

2010

Indium-catalyzed conia-ene reaction and total syntheses of biologically active alkaloids
Takahashi, Keisuke; Hatakeyama, Susumi
Yuki Gosei Kagaku Kyokaishi, 2010, 68 (9), 951-961.

Synthesis and preliminary biological evaluation of 20-epi-eldecalcitol [20-epi-1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3: 20-epi-ED-71]
Hatakeyama, Susumi; Yoshino, Madoka; Eto, Kohei; Takahashi, Keisuke; Ishihara, Jun; Ono, Yoshiyuki; Saito, Hitoshi; Kubodera, Noboru
Journal of Steroid Biochemistry and Molecular Biology,
2010, 121 (1-2), 25-28.

Synthetic studies on vitamin D analogs. 37. Synthesis of 20-epi-1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3: 20-epi-ed-71]
Yoshino, Madoka; Eto, Kohei; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi; Ono, Yoshiyuki; Saito, Hitoshi; Kubodera, Noboru
Heterocycles, 2010, 81 (2), 381-394.

Synthetic study on clutiolide based on a remote chelation controlled Ireland-Claisen rearrangement
Ishihara, Jun; Tokuda, Okihisa; Shiraishi, Kazunori; Nishino, Yukihiro; Takahashi, Keisuke; Hatakeyama, Susumi
Heterocycles, 2010, 80 (2), 1067-1079.

2009

A new variant of Reformatsky-Claisen rearrangement mediated by indium chloride
Ishihara, Jun; Koyama, Noriko; Nishino, Yukihiro; Takahashi, Keisuke; Hatakeyama, Susumi
Synlett, 2009, (14), 2351-2355.

Enantio- and stereoselective route to the phoslactomycin family of antibiotics: formal synthesis of (+)-fostriecin and (+)-phoslactomycin B
Sarkar, Shaheen M.; Wanzala, Everlyne N.; Shibahara, Setsuya; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi
Chemical Communications, 2009, (39), 5907-5909.

Enantioselective route to aryl(1,3-butadien-2-yl)methanols: formal synthesis of (-)-sporochnol A
Yanagimoto, Daisuke; Kawano, Kazuyuki; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi
Heterocycles, 2009, 77 (1), 249-253.

Synthetic studies of vitamin D analogs. Part 35. An improved synthesis of 1-epi-ED-71, a biologically interesting diastereomer of 1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (ED-71)
Eto, Kohei; Fujiyama, Ayako; Kaneko, Mai; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi; Ono, Yoshiyuki; Kubodera, Noboru
Heterocycles, 2009, 77 (1), 323-331.

Total synthesis of (+)-fostriecin and (+)-phoslactomycin B
Shibahara, Setsuya; Fujino, Masataka; Tashiro, Yasumasa; Okamoto, Nanako; Esumi, Tomoyuki; Takahashi, Keisuske; Ishihara, Jun; Hatakeyama, Susumi
Synthesis, 2009, (17), 2935-2953.

2008

Asymmetric synthesis of (+)-trachyspic acid
Morokuma, Kenji; Taira, Yuko; Uehara, Yumiko; Shibahara, Setsuya; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi
Tetrahedron
Letters, 2008, 49 (42), 6043-6045.

Asymmetric Total Synthesis of (+)-Phoslactomycin B
Shibahara, Setsuya; Fujino, Masataka; Tashiro, Yasumasa; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi
Organic Letters, 2008, 10 (11), 2139-2142.

Entry to heterocycles based on indium-catalyzed Conia-ene reactions: asymmetric synthesis of (-)-salinosporamide A
Takahashi, Keisuske; Midori, Michiko; Kawano, Kei; Ishihara, Jun; Hatakeyama, Susumi
Angewandte Chemie, International Edition, 2008, 47 (33), 6244-6246.

Synthetic studies directed toward kaitocephalin: a highly stereocontrolled route to the right-hand pyrrolidine core
Takahashi, Keisuke; Haraguchi, Natsumi; Ishihara, Jun; Hatakeyama, Susumi
Synlett, 2008, (5), 671-674.

2007

A highly stereocontrolled total synthesis of dysiherbaine
Takahashi, Keisuke; Matsumura, Takashi; Ishihara, Jun; Hatakeyama, Susumi
Chemical Communications, 2007, (40), 4158-4160.

Synthesis and biological evaluation of a 3-position epimer of 1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (ED-71)
Hatakeyama, Susumi; Nagashima, Satoshi; Imai, Naoko; Takahashi, Keisuke; Ishihara, Jun; Sugita, Atsuko; Nihei, Takeshi; Saito, Hitoshi; Takahashi, Fumiaki; Kubodera, Noboru
Journal of Steroid Biochemistry and Molecular Biology, 2007, 103 (3-5), 222-226.

Synthesis of 1,3-diepi-ed-71, a biologically important diastereomer of 1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (ED-71)
Fujiyama, Ayako; Kaneko, Mai; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi; Kubodera, Noboru
Heterocycles, 2007, 71 (10), 2263-2271.

Total synthesis of Citrafungin A
Amer, Mumen F. A.; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi
Heterocycles, 2007, 72, 181-185.

Total synthesis of neooxazolomycin
Onyango, Evans Otieno; Tsurumoto, Joji; Imai, Naoko; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi
Angewandte Chemie, International Edition, 2007, 46 (35), 6703-6705.

2006

β-Isocupreidine-Catalyzed Baylis-Hillman Reaction of Chiral N-Boc-α-Amino Aldehydes
Nakano, Ayako; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi
Organic Letters, 2006, 8 (23), 5357-5360.

A Highly Stereocontrolled Total Synthesis of (-)-Neodysiherbaine A
Takahashi, Keisuke; Matsumura, Takashi; Corbin, Graeme R. M.; Ishihara, Jun; Hatakeyama, Susumi
Journal of Organic Chemistry, 2006, 71 (11), 4227-4231.

Synthesis and evaluation of a 3-position diastereomer of 1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (ED-71)
Hatakeyama, Susumi; Nagashima, Satoshi; Imai, Naoko; Takahashi, Keisuke; Ishihara, Jun; Sugita, Atsuko; Nihei, Takeshi; Saito, Hitoshi; Takahashi, Fumiaki; Kubodera, Noboru
Bioorganic & Medicinal Chemistry, 2006, 14 (23), 8050-8056.

Synthesis of putative metabolites of 1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (ED-71)
Ono, Yoshiyuki; Watanabe, Hiroyoshi; Taira, Ikuo; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi; Kubodera, Noboru
Steroids, 2006, 71 (7), 529-540.

Total synthesis of (+)-β-erythroidine
Fukumoto, Hironori; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi
Angewandte Chemie, International Edition, 2006, 45 (17), 2731-2734.

Two convergent approaches to the synthesis of
1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (ED-71) by the lythgoe and the trost coupling reactions
Maeyama, Junji; Hiyamizu, Hiroko; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi; Kubodera, Noboru
Heterocycles, 2006, 70, 295-307.

Two convergent approaches to the synthesis of 1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (ED-71) by the lythgoe and the trost coupling reactions.
Maeyama, Junji; Hiyamizu, Hiroko; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi; Kubodera, Noboru.
Heterocycles, 2006, 70, 295-307.

2005

β-Isocupreidine-hexafluoroisopropyl acrylate method for asymmetric Baylis-Hillman reactions
Nakano, Ayako; Kawahara, Sakie; Akamatsu, Saori; Morokuma, Kenji; Nakatani, Mari; Iwabuchi, Yoshiharu; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi
Tetrahedron, 2005, 62 (2-3), 381-389.

Synthesis of a pseudoenantiomer of β-isocupreidine (β-ICD), a chiral amine catalyst for asymmetric Baylis-Hillman reactions
Nakano, Ayako; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi
Heterocycles, 2005, 66, 371-383.

Total synthesis of viridiofungin A
Morokuma, Kenji; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi
Chemical Communications, 2005, (17), 2265-2267.

2004

A Concise Route to (+)-Lactacystin
Ooi, Hidenori; Ishibashi, Norihisa; Iwabuchi, Yoshiharu; Ishihara, Jun; Hatakeyama, Susumi
Journal of Organic Chemistry, 2004, 69 (22), 7765-7768.

Enantio- and stereocontrolled formation of the bisspiroacetal core of spirolide B
Ishihara, Jun; Ishizaka, Tomoko; Suzuki, Takanori; Hatakeyama, Susumi
Tetrahedron Letters, 2004, 45 (42), 7855-7858.