A new ⁶⁸Ge/⁶⁸Ga generator system using an organic polymer containing N-methylglucamine groups as adsorbent for ⁶⁸Ge.

ABSTRACT
A macroporous styrene-divinylbenzene copolymer containing N-methylglucamine groups was selected for a new ⁶⁸Ge/⁶⁸Ga generator system. This resin packed into a column effectively adsorbed the parent nuclide ⁶⁸Ge. The daughter ⁶⁸Ga was eluted fromthe resin with a solution of a low-affinity galliumchelating ligand such as citric or phosphoric acid. The ⁶⁸Ge leakage was less than 0.0004% of the ⁶⁸Ge adsorbed on the resin. By simple mixing of transferrin and desferoxamine conjugated HSA and IgG with the eluate from the column, ⁶⁸Ga-labeling was completed in high yield.