機能性分子化学研究室
HOME Research Staff Publication

Publication list

2008
Tsutomu Kabashima, Zhiqiang Yu, Chenhong Tang, Yoshiki Nakagawa, Kyosuke Okumura, Takayuki Shibata, Jianzhong Lu, Masaaki Kai: A selective fluorescence reaction for peptides and chromatographic analysis; Peptides, 29, 356-363 (2008).

Keiko Tonooka, Tsutomu Kabashima, Takayuki Shibata, Chenhong Tang, Zhiqiang Yu, and Masaaki Kai: Facile Assay of Telomerase Activity Utilizing a DNA-detectable Chemiluminogenic Reagent; Anal. Sci., 24, 471-475 (2008).

M. N. Wainaina, T. Shibata, C. Smanmoo, T. Kabashima and M. Kai: Fluorescence detection of amino acids in the postcleavage conversions for manual sequencing of a peptide; Anal. Biochem., 374, 423-425 (2008).

2007
H. Zhang, C. Smanmoo, T. Kabashima, J. Lu and M. Kai: Dextran-Based Polymeric Chemiluminescent Compounds for the Sensitive Optical Imaging of a Cytochrome P450 Protein on a Solid-Phase Membrane; Angew. Chem. Int. Ed., 46, 1-5 (2007).

D-Q. Yuan, J. Lu, M. Atumi, J-M. Yan, M. Kai and K. Fujita: Cerium complexes of cyclodextrin dimmers as efficient catalysts for luminol chemiluminescence reactions; Org. Biomol. Chem., 5, 2932-2939 (2007).

K. Tonooka, T. Kabashima, M. Yamasuji and M. Kai: Facile determination of DNA-binding nuclear factor- B by chemiluminescence detection; Anal. Biochem., 364, 30-36 (2007).

2006
K. Ito, Y. Nakajima, Y. Xu, N. Yamada, Y. Onohara, T. Ito, F. Matsubara, T. Kabashima, K. Nakayama and T. Yoshimoto: Crystal structure and mechanism of tripeptidyl activity of prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis; J. Mol. Biol., 362, 228-240 (2006).

Takayuki Shibata, Niklaas J. Buurma, John A. Brazier, Peter Thompson, Ihtshamul Haq, and David M. Williams: 7,8-Dihydropyrido[2,3-d]pyrimidin-2-one; a bicyclic cytosine analogue capable of enhanced stabilisation of DNA duplexes; Chem. Commun., 33, 3516-3518(2006).

Steven J. Pearson, Stephen Wharton, Amanda J. Watson, Ghazala Begum, Amna Butt, Nicola Glynn, David M. Williams, Takayuki Shibata, Mauro F. Santibanez-Koref and Geoffrey P. Margison: A novel DNA damage recognition protein in Schizosaccharomyces pombe; Nucleic Acids Res., 34(8), 2347-2354(2006).

Ana R. Hornillo-Araujo, Adam J. M. Burrell, Miren K. Aiertza, Takayuki Shibata, David M. Hammond, Dolor?s Edmont, Harry Adams, Geoffrey P. Margison and David M. Williams: The syntheses and properties of tricyclic pyrrolo[2,3-d]pyrimidine analogues of S6-methylthioguanine and O6-methylguanine; Org. Biomol. Chem., 4(9), 1723-1729 (2006).

Takayuki Shibata, Nicola Glynn, T. Brian H. McMurry, R. Stanley McElhinney, Geoffrey P. Margison and David M. Williams: Novel synthesis of O6-alkylguanine containing oligodeoxyribonucleotides as substrates for the human DNA repair protein, O6-methylguanine DNA methyltransferase (MGMT); Nucleic Acids Res., 34(6), 1884-1891 (2006).

Xiao Ma, Taizo Kurose, Ella Czarina M. Juan, Takayuki Shibata, David M. Williams, and Akio Takenaka: X-Ray analyses of DNA duplexes stabilized by bicyclic-C residues; Nucleic Acids Symp. Ser., 50, 213-214 (2006).

2005
M. Kai, M. Morizono, M.N. Wainaina, T. Kabashima, M.K. Lee, and J. Lu: Chemiluminescence detection of amino acids using an Edman-type reagent, 4-(1'-cyanoisoindolyl) phenylisothiocyanate; Anal. Chim. Acta , 535, 153-159 (2005).

Zhi-Juan Cao, Ying Xia, Masaaki Kai, Jian-Zhong Lu: Magnetic bead-based label-free chemiluminescence detection of specific DNA sequence-telomere; Acta Chim. Sinica, 63(5), 407-410 (2005).

John A. Brazier, Takayuki Shibata, John Townsley, Brian F. Taylor, Elaine Frary, Nicholas H. Williams and David M. Williams: Amino-functionalized DNA: the properties of C5-amino-alkyl substituted 2'-deoxyuridines and their application in DNA triplex formation; Nucleic Acids Res., 33(4), 1362-1371 (2005).

Takayuki Shibata and David M. Williams: Novel post DNA synthesis chemistry for preparing oligonucleotides containing O6-modified purines; Nucleic Acids Symp. Ser., 49, 23-24 (2005).

2004
C. Lau,J. Lu , M Kai: Chemiluminescence determination of tetracycline based on radical production in a basic acetonitrile-hydrogen peroxide reaction, Anal. Chim. Acta, 503 235-239 (2004).

S. Y. Yin, Y. M. Kim, J. J. Lee, C. M. Jin, Y. J. Yang, J. J. Ma, M. H. Kang, M Kai, M. K. Lee: Enantio-selective inhibition of (1R,9S)-and (1S,9R)-β-hydrastines on dopamine biosynthesis in PC12 cells, Neuropharmacol., 47 1045-1052 (2004).

S. Y. Yin, J. J. Lee, Y. M. Kim, C. M. Jin, Y. J. Yang, M. H. Kang, M Kai, M. K. Lee: Effects of (1R,9S)-β-hydrastine on L-DOPA-induced cytotoxicity in PC12 cells, Euro. J. Pharm., 488 71-77 (2004).

2003
<Research article>
M. Kai, H. Kinoshita, M. Morizono: Chromatographic determinations of a β-lactam antibiotic, cefaclor by means of fluorescence, chemiluminescence and mass spectrometry, Talanta, 60, 325-334 (2003).

J. Lu, C. Lau, M. Kai: Magnetic bead-based label-free chemiluminescence detection of telomeres, Chem. Commun., 2888-2889 (2003).

J. Lu, C. Lau, S. Yagisawa, K. Ohta, M. Kai: A simple and sensitive chemiluminescence method for the determination of tiopronin for a pharmaceutical formulation, J. Pharm. Biomed. Anal., 33, 1033-1038 (2003).

T. Kabasima, T. Kawaguchi, B. E. Wadzinski, K. Uyeda: Xylulose 5-phosphate mediates glucose-induced lipogenesis by xylulose 5-phosphate-activated protein phosphatase in rat liver, Proc. Natl. Acad. Sci. U.S.A., 100, 5107-5112(2003).

2002
<Research article>
C. Lau, J. Lu, T. Yamaguchi, M. Kai: Controlled kinetics of non-enzymatic chemiluminescence reactions for simple imaging of DNA and protein, Anal. Bioanal. Chem., 374, 1064-1068 (2002).

C. Lau, J. Lu, S. Yagisawa, K. Ohta, M. Kai: Simple chemiluminescence method for determination of mercaptopurine, Anal. Sci., 18, 1043-1045 (2002).

D. -Q. Yuan, J. Lu, M. Astimi, A. Izaka, M. Kai, K. Fujita: The first successful investigation into a cyclodextrin-based enzyme model as an efficient catalyst for luminol chemiluminescent reaction, Chem. Commun., 730-731 (2002).

J. Lu, C. Lau, M. K. Lee, M. Kai: Simple and convenienet chemiluminescence method for the determination of melatonin, Anal. Chim. Acta, 455, 193-198 (2002).

M. Kai, H. Kinoshita, K. Ohta, S. Hara, M. K. Lee, J. Lu: Sensitive determination of a β-lactam antibiotic, cefaclor by liquid chromatography with chemiluminescence detection, J. Pharm. Biomed. Anal., 30, 1765-1771 (2002).

T. Kawaguchi, K. Osatomi, H. Yamashita, T. Kabashima, K. Uyeda: Mechanism for fatty acid "sparing"effect on glucose-induced transcription: regulation of carbohydrate-responsive element-binding protein by AMP-activated protein kinase, J. Biol. Chem., 277, 3829-3835(2002).

<Review and Book>
J. Lu, M. Kai: Book review for Chemiluminescence at the Turn of the Millennium, Angew. Chem. Int. Ed., 41, No 5, 865-866 (2002).

2001
<Research article>
J. Lu, C. Lau, M. Morizono, K. Ohta, M. Kai: A chemiluminescence reaction between hydrogen peroxide and acetonitrile and its applications, Anal. Chem., 73, 5979-5983 (2001).

S. H. Kim, J. S. Shin, J. J. Lee, S. Y. Yin, M. Kai, M. K. Lee: Effects of hydrastine derivatives on dopamine biosynthesis in PC12 cells, Planta Med., 67, 609-613 (2001).

S. S. Lee, M. Kai, M. K. Lee: Inhibitory effects of sanguinarine on monoamine oxidase activity in mouse brain, Phytother. Res., 15(2), 167-169 (2001).

M. Tsuchie, S. Hara, M. Kimura, M. Fujii, N. Ono, M. Kai: Determination of anti-virus drug, ganciclovir, in human serum by HPLC with precolumn fluorescence derivatization using phenylglyoxal, Anal. Sci., 17, 811-814 (2001).

T. Kawaguchi, M. Takenoshita, T. Kabashima, K. Uyeda: Glicose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/ dephosphorylation of the carbohydrate reponse element binding protein, Proc. Natl. Acad. U.S.A., 98, 13710-13715(2001).

<Review and Book>
N. Kuroda, M. Kai, K. Nakashima: Chemiluminescence in Analytical Chemistry (Chapter 14, Chemiluminescence detection in liquid chromatography); Ed. by A. M. Garcia-Campana, W. R. G. Baeyens; Marcel dekker, Inc., New York・Basel, pp. 393-425 (2001).

M. Kai, K. Ohta, N. Kuroda, K. Nakashima: Chemiluminescence in Analytical Chemistry (Chapter 19, Chemiluminescence and bioluminescence in DNA analysis); Ed. by A. M. Garcia-Campana, W. R. G. Baeyens; Marcel dekker, Inc., New York・Basel, pp. 551-566 (2001).

2000
<Research article>
Y. Ohba, K. Soda, M. Kai, K. Zaitsu: Assay of cyclic nucleotide phosphodiesterase activity in rat brain by high-performance liquid chromatography using (3,4-dimethoxyphenyl) glyoxal as a fluorescence derivatizing reagent, Anal. Chim. Acta, 414, 95-100 (2000).

J. S. Shin, E. I. Kim, M. Kai, M. K. Lee: Inhibition of dopamine biosynthesis by protoberberine alkaloids in PC12 cells, Neurochem. Res., 25, 363-368 (2000).

A. Toninello, L. Dalla Via, R. Stevanato, S. Yagisawa: Kinetics and free-energy profiles of spermine transport in liver mitochondria, Biochem., 39, 324-331 (2000).

1999
<Research article>
M. Kai, S. Kishida, K. Sakai: A chemiluminescence derivatization method for detecting nucleic acids and DNA probes using a trimethoxyphenylglyoxal reagent that recognizes guanine; Anal. Chim. Acta, 381, 155-163 (1999).

S. S. Lee, M. Kai, M. K. Lee: Effects of natural isoquinolinealkaloids on monoamine oxidase activity in mouse brain: inhibition by berberine and palmatine, Med. Sci. Res., 27, 749-751 (1999).

K.Fujiwara, Y.Masuyama, S.Yagisawa,T.Tanabe, M.Yabuuchi, D.Tsuru: Histamine monoclonal antibody for brain immunocytochemistry, J. Biochem., 126, 503-509 (1999).

K.Fujiwara, I.Murata, S.Yagisawa, T.Tanabe, M.Yabuuchi, R.Sakakibara, D.Tsuru: Glutaraldehyde (GA)-hapten adducts, but without a carrier protein, for use in a specificity study on an antibody against a GA-conjugated hapten compound: Histamine monoclonal antibody (AHA-2) as a model, J. Biochem., 126, 1170-1174 (1999).

<Review and Book>
K. Zaitsu, M. Kai, K. Hamase: ModernDerivatization Methods for Separation Sciences (Chapter 2, Reagent for UV-VIS detection); Ed., T. Toyooka, JohnWiley & Sons Ltd, Chichester, 63-98 (1999).