Research projects
Cell Regulation
- Mechanisms of mitochondrial sensing and stress response
- Mechanisms of inflammatory death of macrophage lineage cells
Pharmacology and Therapeutic Innovation
- Chronic pain and LPA or epigenetic regulation
- Kyotorphin and opioid research
Pharmaceutical Chemistry
- Synthesis of non-natural type amino acids and its application to medicinal chemistry
- Design of cell-penetrating foldamers and their application to drug delivery system
Pharmaceutical Organic Chemistry
- Synthesis of biologically active natural products
- Development of innovative organic reactions and methodologies
Synthetic Chemistry for Pharmaceuticals
- Selective molecular transformation of diols based on molecular recognition
- Highly efficient synthesis of nitrogen heterocycles
Genome-based Drug Discovery
- Analysis of molecular mechanisms underlying the pathogenesis of Alzheimer's disease
- Analysis of endogenous molecules that modulate activities of neprilysin and secretases
Natural Product Chemistry
- Studies on structure, metabolism, function, and application of plant polyphenols)
- Investigation of intra-specific diversity of terpenoids in higher plants
Chemistry of Functional Molecules
- Development of nucleic acid drugs for functional regulation of non-coding RNAs
- Novel drug delivery system using circulating extracellular vehicles
Hygienic Chemistry
- Analysis of selenium component and the effect in fish and shellfishes
- Development of molecular probe for imaging infection in a prion disease
Analytical Chemistry for Pharmaceuticals
- Development of sensitive analytical method for trace levels of biological substances and drugs and their application to clinical chemistry.
- Development and application of specific detection for reactive oxygen species.
Pharmacotherapeutics
- Research into association studies on susceptibility genes for diseases, progression, drug effectiveness, adverse effects, and prognosis using genetic polymorphic markers)
- Research investigating interaction between gut microbiome and metabolic diseases
Pharmaceutical Informatics
- Development of targeted gene delivery system using external stimuli
- Development of nano-biotechnology for medical use
Pharmaceutics
- Drug targeting to the liver utilizing the absorption from the liver surface
- Cell specific gene delivery to the liver by non-viral vector
Pharmacy Practice
- Propose use of PXB-mice® as a reliable tool for drug repositioning screening against liver disease
- Screening disease-specific immune complex antigens for autoimmune diseases and cancers
Molecular Pharmacology of Infectious Agents
- Analysis of mechanism of influenza virus replication
- Analysis of microbial community structure for environmental assessment
Laboratory in Medical Plants Garden
- Studies on the differentiation and material production of plant organization
- Chemo-pharmaceutical studies on the biologically active compounds from marine invertebrates
Structure Analysis for Chemicals
- Research into design and functions of molecular probes for molecular structure analysis
- Exploitation of practical synthetic methodologies and their application for medicinal chemistry
Pharmaceutics and Therapeutics
- Development of novel gene delivery system for clinical use
- Development of vaccine against tropical disease using new delivery technique